MIP and MRPS18B

Data Source:
BioGRID (two hybrid)

		MIP	MRPS18B
Description		major intrinsic protein of lens fiber	mitochondrial ribosomal protein S18B
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Small Ribosomal Subunit Cell Junction
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity	Structural Constituent Of Ribosome Protein Binding
	Biological Process	Lens Development In Camera-type Eye Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport	Translation Mitochondrial Translation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Passive transport by Aquaporins	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs		B-nonylglucoside
Diseases
GWAS		Axial length ( 24144296)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Neuroblastoma (pediatric) ( 32599975) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1	20 interacting genes: BMP10 CD81 CLEC1A ERCC6 EWSR1 EXOSC6 IGFBP5 LAT LRP10 MIP RB1 SEC22B SLC35A1 SYS1 TMED8 TMEM120B TMEM128 TNFRSF10C TRARG1 ZFPL1
Entrez ID		4284	28973
HPRD ID		01098	14781
Ensembl ID		ENSG00000135517	ENSG00000204568
Uniprot IDs		P30301	B0S7P4 Q9Y676
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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