MIP and SYAP1

Data Source:
BioGRID (two hybrid)

		MIP	SYAP1
Description		major intrinsic protein of lens fiber	synapse associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Gap Junction Integral Component Of Membrane Apical Plasma Membrane	Nucleoplasm Golgi Apparatus Cytosol Axon Dendrite Growth Cone Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Presynaptic Membrane Perikaryon Postsynaptic Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Calmodulin Binding Water Channel Activity	Protein Binding
	Biological Process	Lens Development In Camera-type Eye Water Transport Visual Perception Positive Regulation Of Cell Adhesion Response To Stimulus Protein Homotetramerization Transmembrane Transport Gap Junction-mediated Intercellular Transport	Cell Differentiation Cellular Response To Insulin Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus TORC2 Signaling Positive Regulation Of Fat Cell Differentiation Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Protein Serine/threonine Kinase Activity Cellular Response To Insulin-like Growth Factor Stimulus
Pathways		Passive transport by Aquaporins
Drugs		B-nonylglucoside
Diseases
GWAS		Axial length ( 24144296)
Interacting Genes		47 interacting genes: AQP9 ATP6V0B CALM1 CD40 CISD2 CLDN5 CRYAA CRYAB CRYBB2 CRYGC ERGIC3 ERVFRD-1 FAM209A FCGR2A FOXA2 GJA3 GJA8 GJB5 GOLM1 GPX8 KCNJ6 LHFPL5 LMNA LRRC4C MFF MGST3 MRM3 MRPS18B MUC1 PDZK1IP1 PRKACA RELL2 SAR1A SGPL1 SLC14A1 SLC18A1 SSMEM1 STX1A STX2 SYAP1 SYT1 SYT2 TMEM139 TMEM154 TMEM52B TMX2 ZFPL1	6 interacting genes: ADIPOQ MIP POT1 THRA TNFRSF10C ZFPL1
Entrez ID		4284	94056
HPRD ID		01098	06733
Ensembl ID		ENSG00000135517	ENSG00000169895
Uniprot IDs		P30301	Q96A49
PDB IDs			1X3A
Enriched GO Terms of Interacting Partners?
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