MGST3 and MRM1

Data Source:
BioGRID (two hybrid)

		MGST3	MRM1
Description		microsomal glutathione S-transferase 3	mitochondrial rRNA methyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Mitochondrion Mitochondrial Matrix
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding	RNA Binding Protein Binding RRNA (guanosine-2'-O-)-methyltransferase Activity
	Biological Process	Lipid Metabolic Process Xenobiotic Metabolic Process Leukotriene Biosynthetic Process Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	RRNA 2'-O-methylation
Pathways		Glutathione conjugation Aflatoxin activation and detoxification	rRNA modification in the mitochondrion
Drugs		Glutathione
Diseases
GWAS		Metabolite levels ( 23823483) Total ventricular volume ( 21116278)	Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)
Interacting Genes		86 interacting genes: AGPAT4 AGTRAP APOD APOL2 AQP1 AQP10 AQP3 ARL6IP1 ARL6IP6 BET1 BMP10 C11orf24 C14orf180 C3orf52 CACNG1 CCNC CDIPT CLCA4 CLRN1 CMTM5 CREB3L1 CTSA CYBC1 ERG28 F10 FAXDC2 FUNDC2 FXYD6 GIMAP1 GIMAP5 GPR152 GPX8 GRM2 HMOX2 ITGAM LEMD1 LMNA LPAR3 LRP10 MIP MRM1 MTIF3 NEU1 NINJ2 NKG7 NRM NSG1 PAGE1 PLN PLP1 PLP2 PLPP4 SCD SCN3B SEC22B SLC1A3 SLC2A5 SLC35A1 SLC39A9 SLC7A1 SMCO4 SNAP47 SNORC STX3 STX7 STX8 SYS1 TFAM TFRC TMEM107 TMEM109 TMEM120B TMEM140 TMEM229B TMEM60 TMEM86B TMX2 TSPAN12 TSPAN2 TSPAN33 UBIAD1 UNC50 VAMP3 VAMP4 YIF1A ZFPL1	43 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CGGBP1 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1
Entrez ID		4259	79922
HPRD ID		05192	08656
Ensembl ID		ENSG00000143198	ENSG00000278619
Uniprot IDs		A0A024R8Z1 O14880	Q6IN84
PDB IDs
Enriched GO Terms of Interacting Partners?
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