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MIR145 and TIAL1
Data Source:
BioGRID
(unspecified method)
MIR145
TIAL1
Description
microRNA 145
TIA1 cytotoxic granule associated RNA binding protein like 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Lysosome
Cytoplasmic Stress Granule
Ribonucleoprotein Complex
Molecular Function
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
DNA Binding
RNA Binding
Biological Process
Regulation Of Smooth Muscle Contraction
Negative Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Ectodermal Cell Differentiation
Positive Regulation Of Fibroblast Migration
Negative Regulation Of Angiogenesis
Actin Cytoskeleton Organization
Negative Regulation Of Cell Migration
Negative Regulation Of Interleukin-16 Production
Positive Regulation Of Interleukin-10 Production
Regulation Of Collagen Biosynthetic Process
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Vascular Associated Smooth Muscle Cell Differentiation
Myofibroblast Differentiation
Angiotensin-activated Signaling Pathway
Positive Regulation Of Macrophage Activation
Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching
Positive Regulation Of Macrophage Differentiation
Mesodermal Cell Differentiation
Negative Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Inflammatory Response
Negative Regulation Of Protein Kinase B Signaling
Aorta Smooth Muscle Tissue Morphogenesis
Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Phenotypic Switching
Negative Regulation Of Somatic Stem Cell Population Maintenance
Negative Regulation Of Somatic Stem Cell Division
Negative Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Defense Response
Fibroblast Growth Factor Receptor Signaling Pathway
Pathways
FGFR2 alternative splicing
Drugs
Diseases
GWAS
Depressive symptoms (stressful life events interaction) (
27529621
)
Monocyte percentage of white cells (
32888494
)
Parkinson's disease (
27182965
)
Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) (
27047539
)
Interacting Genes
79 interacting genes:
ADARB1
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP6
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
NONO
NUDT16L1
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
PUM1
RARS1
RBM14
RBM4
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYNCRIP
TAF15
TENT2
TIAL1
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
39 interacting genes:
AKAP8L
AOC1
BPIFA1
C10orf55
CAMK2A
CELF4
DAZAP2
FAM168A
FAM168B
FUBP1
GRINA
INCA1
KLF1
KRTAP8-1
MAGED1
MAPK1
MAPK1IP1L
MBNL2
MIR106A
MIR106B
MIR145
MIR199A1
MIR20A
MIR29A
MIR29C
MIR34A
MIR9-2
PRR13
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
QKI
RBPMS2
SMN1
SMN2
SNRPA
VPS37C
Entrez ID
406937
7073
HPRD ID
04563
Ensembl ID
ENSG00000276365
ENSG00000151923
Uniprot IDs
Q01085
Q49AS9
PDB IDs
1X4G
2CQI
2DH7
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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