TIAL1 and AOC1

Data Source:
BioGRID (two hybrid)

		TIAL1	AOC1
Description		TIA1 cytotoxic granule associated RNA binding protein like 1	amine oxidase copper containing 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex	Extracellular Region Extracellular Space Peroxisome Plasma Membrane Bicellular Tight Junction Specific Granule Lumen Extracellular Exosome
	Molecular Function	DNA Binding RNA Binding	Copper Ion Binding Calcium Ion Binding Protein Binding Primary Amine Oxidase Activity Heparin Binding Zinc Ion Binding Protein Homodimerization Activity Protein-containing Complex Binding Quinone Binding Diamine Oxidase Activity Histamine Oxidase Activity Methylputrescine Oxidase Activity Propane-1,3-diamine Oxidase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Fibroblast Growth Factor Receptor Signaling Pathway	Xenobiotic Metabolic Process Amine Metabolic Process Putrescine Metabolic Process Cellular Response To Copper Ion Starvation Neutrophil Degranulation Response To Antibiotic Cellular Response To Copper Ion Cellular Response To Histamine Cellular Response To Heparin Cellular Response To Azide
Pathways		FGFR2 alternative splicing	Phase I - Functionalization of compounds Neutrophil degranulation
Drugs			Amiloride Calcium Diminazene
Diseases
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)	Anthropometric traits (multi-trait analysis) ( 30166351) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 30072576) Carpal tunnel syndrome ( 30833571) Eyebrow thickness ( 26926045) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Serum metabolite concentrations in chronic kidney disease ( 29545352) Triglyceride levels ( 32203549) Triglycerides ( 30275531) Type 2 diabetes ( 30297969) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		39 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C	13 interacting genes: CYB561A3 DAO DAZAP2 DNM2 FGD1 FOXH1 KRTAP8-1 NTAQ1 POGZ RBPMS2 TIAL1 TLX3 ZC3H10
Entrez ID		7073	26
HPRD ID		04563	00088
Ensembl ID		ENSG00000151923	ENSG00000002726
Uniprot IDs		Q01085 Q49AS9	P19801
PDB IDs		1X4G 2CQI 2DH7	3HI7 3HIG 3HII 3K5T 3MPH
Enriched GO Terms of Interacting Partners?
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