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MIR145 and DHX36
Data Source:
BioGRID
(unspecified method)
MIR145
DHX36
Description
microRNA 145
DEAH-box helicase 36
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Exosome
Chromosome, Telomeric Region
Intracellular Anatomical Structure
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Axon
Dendrite
Perikaryon
Extracellular Exosome
Molecular Function
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Magnesium Ion Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
G-quadruplex RNA Binding
DNA Helicase Activity
Single-stranded DNA Binding
RNA Binding
RNA Helicase Activity
Double-stranded RNA Binding
MRNA 3'-UTR Binding
Protein Binding
ATP Binding
DNA-dependent ATPase Activity
MRNA 3'-UTR AU-rich Region Binding
Histone Deacetylase Binding
MRNA 5'-UTR Binding
G-quadruplex DNA Binding
Telomerase RNA Binding
Pre-miRNA Binding
Biological Process
Regulation Of Smooth Muscle Contraction
Negative Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Ectodermal Cell Differentiation
Positive Regulation Of Fibroblast Migration
Negative Regulation Of Angiogenesis
Actin Cytoskeleton Organization
Negative Regulation Of Cell Migration
Negative Regulation Of Interleukin-16 Production
Positive Regulation Of Interleukin-10 Production
Regulation Of Collagen Biosynthetic Process
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Vascular Associated Smooth Muscle Cell Differentiation
Myofibroblast Differentiation
Angiotensin-activated Signaling Pathway
Positive Regulation Of Macrophage Activation
Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching
Positive Regulation Of Macrophage Differentiation
Mesodermal Cell Differentiation
Negative Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Inflammatory Response
Negative Regulation Of Protein Kinase B Signaling
Aorta Smooth Muscle Tissue Morphogenesis
Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Phenotypic Switching
Negative Regulation Of Somatic Stem Cell Population Maintenance
Negative Regulation Of Somatic Stem Cell Division
Negative Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation
Ossification
Positive Regulation Of Myeloid Dendritic Cell Cytokine Production
Regulation Of Transcription By RNA Polymerase III
Spermatogenesis
RNA Secondary Structure Unwinding
Positive Regulation Of Gene Expression
Negative Regulation Of Translation
Positive Regulation Of MRNA 3'-end Processing
Positive Regulation Of Telomere Maintenance
Positive Regulation Of Type I Interferon Production
DNA Duplex Unwinding
Positive Regulation Of Interferon-alpha Production
Cellular Response To Heat
Cellular Response To UV
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Exogenous DsRNA
Regulation Of MRNA Stability
G-quadruplex DNA Unwinding
Innate Immune Response
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Embryonic Development
Defense Response To Virus
Positive Regulation Of Cardioblast Differentiation
Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Dendritic Spine Morphogenesis
3'-UTR-mediated MRNA Destabilization
Telomerase RNA Stabilization
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Positive Regulation Of Hematopoietic Progenitor Cell Differentiation
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Spermatogenesis
Cellular Response To Arsenite Ion
Positive Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Intracellular MRNA Localization
Positive Regulation Of Cytoplasmic Translation
Pathways
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
Drugs
Diseases
GWAS
Blood protein levels (
29875488
)
Body mass index (
29273807
)
Response to cognitive-behavioural therapy in anxiety disorder (
31123309
)
Interacting Genes
79 interacting genes:
ADARB1
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP6
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
NONO
NUDT16L1
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
PUM1
RARS1
RBM14
RBM4
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYNCRIP
TAF15
TENT2
TIAL1
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
71 interacting genes:
DUX4
IL7R
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F2
MIRLET7G
MIRLET7I
TLR1
ZFP36
Entrez ID
406937
170506
HPRD ID
09918
Ensembl ID
ENSG00000276365
ENSG00000174953
Uniprot IDs
Q9H2U1
PDB IDs
2N16
2N21
6Q6R
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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