TIAL1 and MIR20A

Data Source:
BioGRID (unspecified method)

		TIAL1	MIR20A
Description		TIA1 cytotoxic granule associated RNA binding protein like 1	microRNA 20a
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex	Extracellular Space Extracellular Vesicle
	Molecular Function	DNA Binding RNA Binding	RNA Polymerase II Complex Binding MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Fibroblast Growth Factor Receptor Signaling Pathway	Outflow Tract Morphogenesis Negative Regulation Of Protein Kinase Activity Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Interleukin-17 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Cell Adhesion Molecule Production Cellular Response To Lipopolysaccharide Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of P38MAPK Cascade Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Cardioblast Proliferation Positive Regulation Of Pulmonary Blood Vessel Remodeling
Pathways		FGFR2 alternative splicing
Drugs
Diseases
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)
Interacting Genes		39 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C	73 interacting genes: AIMP2 APOBEC3B C1QBP CRTAP DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DZIP3 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC LSM10 LSM11 MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SFPQ SUGP2 SYNCRIP TAF15 TIAL1 TRA2A TRA2B UPF1 UTP20 YBX1 YBX3 ZNF346
Entrez ID		7073	406982
HPRD ID		04563
Ensembl ID		ENSG00000151923	ENSG00000283762
Uniprot IDs		Q01085 Q49AS9
PDB IDs		1X4G 2CQI 2DH7
Enriched GO Terms of Interacting Partners?
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