TIAL1 and FAM168B

Data Source:
BioGRID (two hybrid)

		TIAL1	FAM168B
Description		TIA1 cytotoxic granule associated RNA binding protein like 1	family with sequence similarity 168 member B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex	Plasma Membrane Integral Component Of Membrane Axon Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	DNA Binding RNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Fibroblast Growth Factor Receptor Signaling Pathway
Pathways		FGFR2 alternative splicing
Drugs
Diseases
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)
Interacting Genes		39 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C	51 interacting genes: AGXT ARID5A BAG3 CAMK2A CCNK CSTF2 CSTF2T EGLN3 FAM168A FAM222B FOXH1 FOXI1 GLIS2 GPS2 HOXB9 HSF4 KRTAP26-1 LASP1 MED25 MSRB3 MYOZ3 NEDD9 OTX1 PATZ1 PITX1 POGZ POM121 PPP1R32 PRR35 RAMAC RBFOX2 RHOXF2 ROR2 SAMD7 SNRPB SNRPC SPAG8 TCF7L2 TENT5B TIAL1 TLE5 TLX3 UBAP2 VENTX VEZF1 VGLL3 VPS37C WDR25 YPEL3 ZC3H10 ZIC1
Entrez ID		7073	130074
HPRD ID		04563	17295
Ensembl ID		ENSG00000151923	ENSG00000152102
Uniprot IDs		Q01085 Q49AS9	A0A024QZ31 A1KXE4
PDB IDs		1X4G 2CQI 2DH7
Enriched GO Terms of Interacting Partners?
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