TIAL1 and FUBP1

Data Source:
BioGRID (two hybrid)

		TIAL1	FUBP1
Description		TIA1 cytotoxic granule associated RNA binding protein like 1	far upstream element binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Lysosome Cytoplasmic Stress Granule Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding RNA Binding	Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Defense Response Fibroblast Growth Factor Receptor Signaling Pathway	Regulation Of Gene Expression Positive Regulation Of Gene Expression
Pathways		FGFR2 alternative splicing
Drugs			Irofulven Sacituzumab govitecan
Diseases
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Monocyte percentage of white cells ( 32888494) Parkinson's disease ( 27182965) Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)	BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Lung cancer in never smokers ( 28604730) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Psoriasis ( 28537254)
Interacting Genes		39 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C	25 interacting genes: AIMP2 ANXA11 CCNH CELF1 CHD3 CRMP1 ESR1 GTF2H1 IMMT MAPK1IP1L MYOC PRPF40B PRR13 PUF60 SIRPA SMN1 SMURF2 SNRPA SNRPB SNRPC TIAL1 TLE1 U2AF2 VIM VPS37C
Entrez ID		7073	8880
HPRD ID		04563	10349
Ensembl ID		ENSG00000151923	ENSG00000162613
Uniprot IDs		Q01085 Q49AS9	A0A384MDX9 B4DT31 Q96AE4
PDB IDs		1X4G 2CQI 2DH7	1J4W 2KXH 4LIJ 6Y24 6Y2C 6Y2D
Enriched GO Terms of Interacting Partners?
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