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MIR145 and PGAM5
Data Source:
BioGRID
(unspecified method)
MIR145
PGAM5
Description
microRNA 145
PGAM family member 5, mitochondrial serine/threonine protein phosphatase
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Exosome
Mitochondrion
Mitochondrial Outer Membrane
Integral Component Of Membrane
Molecular Function
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Protein Serine/threonine Phosphatase Activity
GTPase Activator Activity
Protein Binding
Phosphatase Activity
Protein-containing Complex Binding
Protein Serine Phosphatase Activity
Protein Threonine Phosphatase Activity
Biological Process
Regulation Of Smooth Muscle Contraction
Negative Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Ectodermal Cell Differentiation
Positive Regulation Of Fibroblast Migration
Negative Regulation Of Angiogenesis
Actin Cytoskeleton Organization
Negative Regulation Of Cell Migration
Negative Regulation Of Interleukin-16 Production
Positive Regulation Of Interleukin-10 Production
Regulation Of Collagen Biosynthetic Process
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Vascular Associated Smooth Muscle Cell Differentiation
Myofibroblast Differentiation
Angiotensin-activated Signaling Pathway
Positive Regulation Of Macrophage Activation
Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching
Positive Regulation Of Macrophage Differentiation
Mesodermal Cell Differentiation
Negative Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Inflammatory Response
Negative Regulation Of Protein Kinase B Signaling
Aorta Smooth Muscle Tissue Morphogenesis
Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Phenotypic Switching
Negative Regulation Of Somatic Stem Cell Population Maintenance
Negative Regulation Of Somatic Stem Cell Division
Negative Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation
Protein Dephosphorylation
Macroautophagy
Positive Regulation Of GTPase Activity
Necroptotic Process
Negative Regulation Of Cold-induced Thermogenesis
Pathways
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Interacting Genes
79 interacting genes:
ADARB1
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP6
LARP7
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
NONO
NUDT16L1
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
PUM1
RARS1
RBM14
RBM4
RTCA
RTCB
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYNCRIP
TAF15
TENT2
TIAL1
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
30 interacting genes:
HSPA1B
MIR106A
MIR106B
MIR107
MIR10B
MIR128-1
MIR141
MIR145
MIR15A
MIR16-1
MIR18B
MIR200B
MIR205
MIR206
MIR20B
MIR21
MIR214
MIR25
MIR34A
MIR451A
MIR93
MIRLET7A1
MIRLET7A2
MIRLET7B
MIRLET7E
MIRLET7F1
SETDB1
UBE4B
YWHAG
ZBTB16
Entrez ID
406937
192111
HPRD ID
14681
Ensembl ID
ENSG00000276365
ENSG00000247077
Uniprot IDs
Q96HS1
PDB IDs
3MXO
3O0T
5MUF
6CNI
6CNL
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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