PGAM5 and MIR25

Data Source:
BioGRID (unspecified method)

		PGAM5	MIR25
Description		PGAM family member 5, mitochondrial serine/threonine protein phosphatase	microRNA 25
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane	Extracellular Space
	Molecular Function	Protein Serine/threonine Phosphatase Activity GTPase Activator Activity Protein Binding Phosphatase Activity Protein-containing Complex Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Protein Dephosphorylation Macroautophagy Positive Regulation Of GTPase Activity Necroptotic Process Negative Regulation Of Cold-induced Thermogenesis	Gene Silencing By MiRNA Negative Regulation Of Cardiac Muscle Tissue Growth Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		30 interacting genes: HSPA1B MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR141 MIR145 MIR15A MIR16-1 MIR18B MIR200B MIR205 MIR206 MIR20B MIR21 MIR214 MIR25 MIR34A MIR451A MIR93 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7E MIRLET7F1 SETDB1 UBE4B YWHAG ZBTB16	100 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC5L CELF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 ELAC1 EPRS1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PATL1 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM17 RBM4 RBM45 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM25 TRIM56 TRIM71 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3
Entrez ID		192111	407014
HPRD ID		14681
Ensembl ID		ENSG00000247077	ENSG00000207547
Uniprot IDs		Q96HS1
PDB IDs		3MXO 3O0T 5MUF 6CNI 6CNL
Enriched GO Terms of Interacting Partners?
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