PGAM5 and MIR128-1

Data Source:
BioGRID (unspecified method)

		PGAM5	MIR128-1
Description		PGAM family member 5, mitochondrial serine/threonine protein phosphatase	microRNA 128-1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane	Extracellular Space
	Molecular Function	Protein Serine/threonine Phosphatase Activity GTPase Activator Activity Protein Binding Phosphatase Activity Protein-containing Complex Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Protein Dephosphorylation Macroautophagy Positive Regulation Of GTPase Activity Necroptotic Process Negative Regulation Of Cold-induced Thermogenesis	Positive Regulation Of Protein Phosphorylation Negative Regulation Of Lipoprotein Particle Clearance Gene Silencing By MiRNA Cholesterol Homeostasis Lipid Homeostasis Negative Regulation Of Cholesterol Efflux Negative Regulation Of Lipoprotein Transport Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Microglial Cell Activation
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Body mass index ( 26426971)
Interacting Genes		30 interacting genes: HSPA1B MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR141 MIR145 MIR15A MIR16-1 MIR18B MIR200B MIR205 MIR206 MIR20B MIR21 MIR214 MIR25 MIR34A MIR451A MIR93 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7E MIRLET7F1 SETDB1 UBE4B YWHAG ZBTB16	91 interacting genes: AIMP1 AIMP2 APOBEC3B ATXN2 ATXN2L C1QBP CASC3 CELF1 CPSF6 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC LSM10 LSM11 MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM17 RBM4 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR
Entrez ID		192111	406915
HPRD ID		14681
Ensembl ID		ENSG00000247077	ENSG00000207654
Uniprot IDs		Q96HS1
PDB IDs		3MXO 3O0T 5MUF 6CNI 6CNL
Enriched GO Terms of Interacting Partners?
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