PGAM5 and MIR200B

Data Source:
BioGRID (unspecified method)

		PGAM5	MIR200B
Description		PGAM family member 5, mitochondrial serine/threonine protein phosphatase	microRNA 200b
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Integral Component Of Membrane
	Molecular Function	Protein Serine/threonine Phosphatase Activity GTPase Activator Activity Protein Binding Phosphatase Activity Protein-containing Complex Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Protein Dephosphorylation Macroautophagy Positive Regulation Of GTPase Activity Necroptotic Process Negative Regulation Of Cold-induced Thermogenesis	Positive Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Myotube Differentiation Negative Regulation Of Angiogenesis Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Vascular Wound Healing Positive Regulation Of Cell Cycle Arrest Negative Regulation Of Interleukin-33 Production Negative Regulation Of Cardiac Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		30 interacting genes: HSPA1B MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR141 MIR145 MIR15A MIR16-1 MIR18B MIR200B MIR205 MIR206 MIR20B MIR21 MIR214 MIR25 MIR34A MIR451A MIR93 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7E MIRLET7F1 SETDB1 UBE4B YWHAG ZBTB16	83 interacting genes: ADARB1 APOBEC3B AQR C1QBP CDC5L CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PTCD3 PUF60 PUM1 QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346
Entrez ID		192111	406984
HPRD ID		14681
Ensembl ID		ENSG00000247077	ENSG00000207730
Uniprot IDs		Q96HS1
PDB IDs		3MXO 3O0T 5MUF 6CNI 6CNL
Enriched GO Terms of Interacting Partners?
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