CEP44 and ING5

Data Source:
BioGRID (two hybrid)

		CEP44	ING5
Description		centrosomal protein 44	inhibitor of growth family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Centriole Midbody	Histone Acetyltransferase Complex Nucleus Nucleoplasm Chromosome MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Microtubule Binding	Chromatin Binding Protein Binding Methylated Histone Binding Metal Ion Binding
	Biological Process	Centrosome Cycle Centriole Replication Centriole-centriole Cohesion	DNA Replication Protein Acetylation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Apoptotic Signaling Pathway
Pathways			HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS			Asthma ( 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet distribution width ( 32888494)
Interacting Genes		54 interacting genes: ABI2 ABI3 ANKRD11 AQP1 BEND7 BFSP2 BLOC1S6 BYSL CAB39 CBY2 CCDC116 CCDC146 CCDC185 CDC23 CENPP CEP57L1 CHIC2 DCTN2 DHX57 DIP2A ERAL1 FAM161A FAM74A4 FXR2 GNG11 H2AP HAUS1 ING5 KIAA0930 LINC02363 LMO1 LRRFIP1 MAPK9 MCRS1 MLLT6 MRFAP1L1 NAA10 PLEKHF2 POLR3C POP5 PSMD3 RBM15 RECK RNF8 SCNM1 TCEA2 TRIM41 TSGA10 TXLNA ZFYVE26 ZNF250 ZNF417 ZNF587 ZNF688	47 interacting genes: APC APLP1 ARFIP2 BARD1 BEX3 BRPF1 C3orf62 CBY2 CCDC33 CCHCR1 CDCA7L CDK2 CDKN1A CEP126 CEP44 DEUP1 EP300 FAM118B GCSH GGA1 GRIPAP1 HAP1 HGS HTT ICA1 IKZF3 JADE2 KRT40 KRTAP10-7 KXD1 MBIP MCM6 MEST NAV2 ODF2 PCM1 PRMT5 RCOR3 SMARCE1 SUOX TADA3 TAF1D THAP6 TP53 TRIML2 VIM WASF1
Entrez ID		80817	84289
HPRD ID		13885	16348
Ensembl ID		ENSG00000164118	ENSG00000168395
Uniprot IDs		Q9C0F1	A0A1B0GW41 Q8WYH8
PDB IDs			3C6W 5ME8 5MTO
Enriched GO Terms of Interacting Partners?
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