CEP44 and LRRFIP1

Data Source:
BioGRID (two hybrid)

		CEP44	LRRFIP1
Description		centrosomal protein 44	LRR binding FLII interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Centriole Midbody	Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane
	Molecular Function	Protein Binding Microtubule Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Double-stranded RNA Binding Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Centrosome Cycle Centriole Replication Centriole-centriole Cohesion	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Type I Interferon Production Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways			Signaling by cytosolic FGFR1 fusion mutants LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Signaling by FGFR1 in disease
Drugs
Diseases
GWAS			Adiposity ( 23505185) Apolipoprotein A1 levels ( 32203549) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Longevity ( 30294719)
Interacting Genes		54 interacting genes: ABI2 ABI3 ANKRD11 AQP1 BEND7 BFSP2 BLOC1S6 BYSL CAB39 CBY2 CCDC116 CCDC146 CCDC185 CDC23 CENPP CEP57L1 CHIC2 DCTN2 DHX57 DIP2A ERAL1 FAM161A FAM74A4 FXR2 GNG11 H2AP HAUS1 ING5 KIAA0930 LINC02363 LMO1 LRRFIP1 MAPK9 MCRS1 MLLT6 MRFAP1L1 NAA10 PLEKHF2 POLR3C POP5 PSMD3 RBM15 RECK RNF8 SCNM1 TCEA2 TRIM41 TSGA10 TXLNA ZFYVE26 ZNF250 ZNF417 ZNF587 ZNF688	6 interacting genes: CEP44 FBXO7 FLII MED4 SERPINB5 SH2D2A
Entrez ID		80817	9208
HPRD ID		13885	04460
Ensembl ID		ENSG00000164118	ENSG00000124831
Uniprot IDs		Q9C0F1	A0A0F7NGI8 B4DPC0 Q32MZ4
PDB IDs			4H22
Enriched GO Terms of Interacting Partners?
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