IHO1 and TRIM14

Data Source:
BioGRID (two hybrid)

		IHO1	TRIM14
Description		interactor of HORMAD1 1	tripartite motif containing 14
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome	Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Cytosol Phagocytic Vesicle
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Regulation Of Homologous Chromosome Segregation	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS			Multiple sclerosis ( 31604244)
Interacting Genes		78 interacting genes: ABI2 ABI3 ADAMTS12 AQP1 ARHGEF9 ATP6V0D1 BCL6 BOLA2 BOLA2B C1orf109 CARD9 CCDC120 CCDC57 CDC23 CFAP206 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 EXOC8 FAM124A FAM124B FANCG FANCL FASLG FHL3 FKBP6 GEM GLRX3 GLYCTK GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KIF9 KIFC3 KLC3 KLHL11 LMO2 LNX1 LONRF1 MAGEB4 MAGOHB MAPK9 MID2 MRFAP1L1 MVP MYO15B NEK6 NFKBID NGB PICK1 POLR1C PRKAB2 PRR34 RABGEF1 RAD51D RHOBTB3 RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM14 TRIM42 TTC19 USP2 USP20 ZGPAT ZKSCAN3 ZNF417 ZNF688	84 interacting genes: ABCF3 ADAMTS12 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H BYSL CARD9 CCDC125 CCDC57 CCDC6 CENPC CIB3 CKS1B CSPP1 EIF3G ERCC3 ETFBKMT EXOC8 FAM50B FAT1 GOLGA2 GOLGA6L9 HERC3 HEXIM2 HNRNPF IHO1 ITM2A IVNS1ABP KAT2B KIF3A KIFC3 LAMTOR1 LNX1 MAPRE3 MITD1 MNAT1 MRPL24 MYO15B NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR1C POLR2G PPP2R3C PRDM6 PRKAB2 PRPF31 PTPN21 RAB5A RAB9A RAD51D RBM33 RLF RNF125 RNF20 SLF2 SMARCB1 SMIM3 SPG21 STK38 TAX1BP1 TMEM167A TRAF2 TSGA10 UBE2B UBE2N UNK VIM WDR35 WRNIP1 ZC4H2 ZFP36L2 ZGPAT ZNF652
Entrez ID		339834	9830
HPRD ID		14172	05948
Ensembl ID		ENSG00000173421	ENSG00000106785
Uniprot IDs		B4DZP6 Q8IYA8	A0A024R165 Q14142
PDB IDs			6JBM
Enriched GO Terms of Interacting Partners?
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