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GSN and CLIC5
Data Source:
HPRD
(in vitro)
GSN
CLIC5
Description
gelsolin
chloride intracellular channel 5
Image
GO Annotations
Cellular Component
Ruffle
Podosome
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Focal Adhesion
Actin Cytoskeleton
Sarcoplasm
Lamellipodium
Actin Cap
Cortical Actin Cytoskeleton
Protein-containing Complex
Secretory Granule Lumen
Myelin Sheath
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Blood Microparticle
Ficolin-1-rich Granule Lumen
Golgi Apparatus
Microtubule Organizing Center
Cell Cortex
Actin Cytoskeleton
Apical Plasma Membrane
Chloride Channel Complex
Extracellular Exosome
Molecular Function
Actin Binding
Calcium Ion Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Phosphatidylinositol 3-kinase Catalytic Subunit Binding
Myosin II Binding
Actin Filament Binding
Voltage-gated Ion Channel Activity
Chloride Channel Activity
Protein Binding
Biological Process
Phagocytosis, Engulfment
Central Nervous System Development
Aging
Actin Polymerization Or Depolymerization
Positive Regulation Of Gene Expression
Oligodendrocyte Development
Striated Muscle Atrophy
Extracellular Matrix Disassembly
Cell Projection Assembly
Actin Filament Polymerization
Actin Filament Depolymerization
Regulation Of Cell Adhesion
Protein Destabilization
Response To Muscle Stretch
Wound Healing
Tissue Regeneration
Sequestering Of Actin Monomers
Neutrophil Degranulation
Cellular Protein Metabolic Process
Actin Nucleation
Response To Ethanol
Negative Regulation Of Viral Entry Into Host Cell
Phosphatidylinositol-mediated Signaling
Actin Filament Severing
Barbed-end Actin Filament Capping
Positive Regulation Of Actin Nucleation
Response To Folic Acid
Actin Filament Capping
Relaxation Of Cardiac Muscle
Cilium Assembly
Cellular Response To Cadmium Ion
Cellular Response To Interferon-gamma
Regulation Of Podosome Assembly
Cardiac Muscle Cell Contraction
Actin Filament Reorganization
Renal Protein Absorption
Hepatocyte Apoptotic Process
Positive Regulation Of Keratinocyte Apoptotic Process
Regulation Of Establishment Of T Cell Polarity
Regulation Of Plasma Membrane Raft Polarization
Regulation Of Receptor Clustering
Positive Regulation Of Protein Processing In Phagocytic Vesicle
Amyloid Fibril Formation
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Glutathione Metabolic Process
Chloride Transport
Female Pregnancy
Visual Perception
Sensory Perception Of Sound
Regulation Of Ion Transmembrane Transport
Response To Stimulus
Chloride Transmembrane Transport
Pathways
Caspase-mediated cleavage of cytoskeletal proteins
Neutrophil degranulation
Amyloid fiber formation
Drugs
Zinc
Latrunculin A
Copper
Zinc acetate
Diseases
Lattice corneal dystrophies (LCD), including: Biber-Haab-Dimmer dystrophy; Familial amyloid polyneuropathy type IV; Meretoja syndrome
Familial amyloidosis
GWAS
Blood protein levels (
30072576
)
Blond vs. brown/black hair color (
30531825
)
Blood protein levels (
30072576
29875488
)
Cerebrospinal AB1-42 levels in normal cognition (
29274321
)
Gout (normal type) (
32238385
)
Heel bone mineral density (
30598549
)
Intraocular pressure (
29785010
)
Itch intensity from mosquito bite (
28199695
)
Mosquito bite size (
28199695
)
Periodontal microbiota (
22699663
)
Interacting Genes
24 interacting genes:
ACTA1
ACTB
ACTG1
ACTN4
APP
AR
BCAR1
CASP3
CLIC5
CSK
ERBB2
FHIT
FN1
LIMK2
PIK3CG
PLCG1
PTK2B
PXN
STK39
TNIK
TOM1L1
VASP
VCL
VDAC1
8 interacting genes:
ACTA1
ACTN1
EZR
GSN
IQGAP1
LAMTOR5
SRPK1
TPRN
Entrez ID
2934
53405
HPRD ID
00674
06292
Ensembl ID
ENSG00000148180
ENSG00000112782
Uniprot IDs
A0A0A0MS51
A0A0A0MT01
A0A384MEF1
B7Z4U6
P06396
Q49AE1
Q53G01
Q9NZA1
PDB IDs
1C0F
1C0G
1D4X
1DEJ
1EQY
1ESV
1H1V
1KCQ
1MDU
1NLV
1NM1
1NMD
1P8X
1P8Z
1SOL
1T44
1YAG
1YVN
2FF3
2FF6
2FH1
2FH2
2FH3
2FH4
3A5L
3A5M
3A5N
3A5O
3CI5
3CIP
3CJB
3CJC
3FFK
3FFN
3TU5
4PKG
4PKH
4PKI
4S10
4Z94
5DD2
5FAE
5FAF
5H3M
5H3N
5O2Z
5UBO
5ZZ0
6H1F
6JCO
6JEG
6JEH
6LJE
6LJF
6Q9R
6Q9Z
6QBF
6QW3
6Y2H
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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