ATXN10 and HTR6

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ATXN10	HTR6
Description		ataxin 10	5-hydroxytryptamine receptor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Plasma Membrane Membrane Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Cilium Dendrite Synapse
	Molecular Function	Protein Binding Enzyme Binding Identical Protein Binding	Histamine Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity
	Biological Process	Nervous System Development Neuron Projection Development Cilium Assembly	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Cerebral Cortex Cell Migration Positive Regulation Of TOR Signaling G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Serotonin receptors G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs			Ziprasidone Amitriptyline Olanzapine Clozapine Loxapine Imipramine Chlorpromazine Haloperidol Amoxapine Paroxetine Cyclobenzaprine Ergoloid mesylate Doxepin Quetiapine Aripiprazole Chlorprothixene Dimethyltryptamine Lysergic acid diethylamide Iloperidone SGS518 PRX-07034 SUVN-502 Sertindole Mianserin Asenapine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Blond vs. brown/black hair color ( 30531825) Heel bone mineral density ( 30598549) Hematocrit ( 29403010) Hemoglobin ( 29403010) Hip circumference ( 28552196) Waist circumference ( 28552196)	Chronotype ( 26955885 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 27494321)
Interacting Genes		12 interacting genes: ABCA1 FN1 GLS GNB1 GNB2 GOLGA1 HSPB1 HTR6 LIMS1 MRPS16 PPP1R12A PTGER4	31 interacting genes: ABCA2 ACTB AIP AKR1A1 AP2M1 AP4S1 ATXN10 CHN1 CMSS1 COPS5 DDRGK1 DHRS1 EIF4A3 FYN GNAQ GNAS HDGFL2 IDS MAP1B NF1 NRXN3 PARP8 RUNDC3A SCHIP1 SLC6A1 SRRT SYT5 THY1 TMEM98 TTYH1 UQCRFS1
Entrez ID		25814	3362
HPRD ID		04624	03066
Ensembl ID		ENSG00000130638	ENSG00000158748
Uniprot IDs		Q9UBB4	P50406
PDB IDs
Enriched GO Terms of Interacting Partners?
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