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HTR6 and IDS
Data Source:
BioGRID
(two hybrid)
HTR6
IDS
Description
5-hydroxytryptamine receptor 6
iduronate 2-sulfatase
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Cilium
Dendrite
Synapse
Lysosome
Lysosomal Lumen
Molecular Function
Histamine Receptor Activity
G Protein-coupled Serotonin Receptor Activity
Protein Binding
Neurotransmitter Receptor Activity
Iduronate-2-sulfatase Activity
Calcium Ion Binding
Sulfuric Ester Hydrolase Activity
Biological Process
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Chemical Synaptic Transmission
Cerebral Cortex Cell Migration
Positive Regulation Of TOR Signaling
G Protein-coupled Serotonin Receptor Signaling Pathway
Glycosaminoglycan Catabolic Process
Chondroitin Sulfate Catabolic Process
Pathways
Serotonin receptors
G alpha (s) signalling events
ADORA2B mediated anti-inflammatory cytokines production
HS-GAG degradation
CS/DS degradation
MPS II - Hunter syndrome
Drugs
Ziprasidone
Amitriptyline
Olanzapine
Clozapine
Loxapine
Imipramine
Chlorpromazine
Haloperidol
Amoxapine
Paroxetine
Cyclobenzaprine
Ergoloid mesylate
Doxepin
Quetiapine
Aripiprazole
Chlorprothixene
Dimethyltryptamine
Lysergic acid diethylamide
Iloperidone
SGS518
PRX-07034
SUVN-502
Sertindole
Mianserin
Asenapine
Zotepine
Setiptiline
Dihydroergocornine
Gilteritinib
Tiapride
Dihydroergocristine
Aripiprazole lauroxil
Diseases
Mucopolysaccharidosis type II (MPS2); Hunter syndrome
GWAS
Chronotype (
26955885
27494321
)
Morning person (
30696823
)
Morning vs. evening chronotype (
26955885
27494321
)
Cognitive performance (
20125193
)
Idiopathic downbeat nystagmus (
32157568
)
Interacting Genes
31 interacting genes:
ABCA2
ACTB
AIP
AKR1A1
AP2M1
AP4S1
ATXN10
CHN1
CMSS1
COPS5
DDRGK1
DHRS1
EIF4A3
FYN
GNAQ
GNAS
HDGFL2
IDS
MAP1B
NF1
NRXN3
PARP8
RUNDC3A
SCHIP1
SLC6A1
SRRT
SYT5
THY1
TMEM98
TTYH1
UQCRFS1
1 interacting genes:
HTR6
Entrez ID
3362
3423
HPRD ID
03066
02402
Ensembl ID
ENSG00000158748
ENSG00000010404
Uniprot IDs
P50406
B4DGD7
P22304
PDB IDs
5FQL
6IOZ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
?
Tagcloud (Intersection)
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