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HTR6 and THY1
Data Source:
BioGRID
(two hybrid)
HTR6
THY1
Description
5-hydroxytryptamine receptor 6
Thy-1 cell surface antigen
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Cilium
Dendrite
Synapse
Extracellular Region
Endoplasmic Reticulum
Plasma Membrane
Integral Component Of Plasma Membrane
Focal Adhesion
External Side Of Plasma Membrane
Cell Surface
Apical Plasma Membrane
Dendrite
Growth Cone
Axolemma
Anchored Component Of External Side Of Plasma Membrane
Dendrite Membrane
Neuronal Cell Body Membrane
Membrane Raft
Extracellular Exosome
Molecular Function
Histamine Receptor Activity
G Protein-coupled Serotonin Receptor Activity
Protein Binding
Neurotransmitter Receptor Activity
GTPase Activator Activity
Integrin Binding
Protein Binding
Protein Kinase Binding
GPI Anchor Binding
Biological Process
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Chemical Synaptic Transmission
Cerebral Cortex Cell Migration
Positive Regulation Of TOR Signaling
G Protein-coupled Serotonin Receptor Signaling Pathway
Angiogenesis
Regulation Of Cell-matrix Adhesion
Positive Regulation Of Cellular Extravasation
Negative Regulation Of Protein Kinase Activity
Cytoskeleton Organization
Integrin-mediated Signaling Pathway
Cell-cell Signaling
Negative Regulation Of Cell Migration
Positive Regulation Of Heterotypic Cell-cell Adhesion
Receptor Clustering
Positive Regulation Of GTPase Activity
Retinal Cone Cell Development
Focal Adhesion Assembly
Negative Regulation Of Axonogenesis
T Cell Receptor Signaling Pathway
Negative Regulation Of T Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Activation
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Focal Adhesion Assembly
Negative Regulation Of Protein Tyrosine Kinase Activity
Negative Regulation Of Neuron Projection Regeneration
Cell-cell Adhesion
Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity
Pathways
Serotonin receptors
G alpha (s) signalling events
ADORA2B mediated anti-inflammatory cytokines production
Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Ziprasidone
Amitriptyline
Olanzapine
Clozapine
Loxapine
Imipramine
Chlorpromazine
Haloperidol
Amoxapine
Paroxetine
Cyclobenzaprine
Ergoloid mesylate
Doxepin
Quetiapine
Aripiprazole
Chlorprothixene
Dimethyltryptamine
Lysergic acid diethylamide
Iloperidone
SGS518
PRX-07034
SUVN-502
Sertindole
Mianserin
Asenapine
Zotepine
Setiptiline
Dihydroergocornine
Gilteritinib
Tiapride
Dihydroergocristine
Aripiprazole lauroxil
Diseases
GWAS
Chronotype (
26955885
27494321
)
Morning person (
30696823
)
Morning vs. evening chronotype (
26955885
27494321
)
Refractive error (
32231278
)
Interacting Genes
31 interacting genes:
ABCA2
ACTB
AIP
AKR1A1
AP2M1
AP4S1
ATXN10
CHN1
CMSS1
COPS5
DDRGK1
DHRS1
EIF4A3
FYN
GNAQ
GNAS
HDGFL2
IDS
MAP1B
NF1
NRXN3
PARP8
RUNDC3A
SCHIP1
SLC6A1
SRRT
SYT5
THY1
TMEM98
TTYH1
UQCRFS1
10 interacting genes:
ATXN1L
ATXN7
CCR8
CLK1
FYN
HTR6
ITGAM
ITGAV
ITGB3
LCK
Entrez ID
3362
7070
HPRD ID
03066
01769
Ensembl ID
ENSG00000158748
ENSG00000154096
Uniprot IDs
P50406
B0YJA4
P04216
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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