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TMEM86B and GJA8
Data Source:
BioGRID
(two hybrid)
TMEM86B
GJA8
Description
transmembrane protein 86B
gap junction protein alpha 8
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Integral Component Of Plasma Membrane
Connexin Complex
Molecular Function
Protein Binding
Ether Hydrolase Activity
Identical Protein Binding
Alkenylglycerophosphocholine Hydrolase Activity
Alkenylglycerophosphoethanolamine Hydrolase Activity
Gap Junction Channel Activity
Protein Binding
Identical Protein Binding
Biological Process
Phosphatidylcholine Acyl-chain Remodeling
Ether Lipid Metabolic Process
Lens Development In Camera-type Eye
Cell-cell Signaling
Transmembrane Transport
Gap Junction-mediated Intercellular Transport
Pathways
Acyl chain remodelling of PC
Gap junction assembly
Drugs
Diseases
GWAS
Mean reticulocyte volume (
32888494
)
Phosphatidylethanolamine-ether levels (
31551469
)
Systemic lupus erythematosus (
33536424
28714469
)
Retinopathy x type 2 diabetes interaction (
32541925
)
Interacting Genes
105 interacting genes:
AQP6
ARL13B
ARL6IP6
ASGR2
BCL2L13
BIK
BMP10
C2CD2L
CCDC167
CCDC34
CCL4
CD53
CD79A
CLRN1
CYB5B
DHRSX
DNAJC30
EBP
ERGIC3
ERP29
EVI2B
F11R
FAM209A
FAXDC2
FKBP7
FXYD6
GJA1
GJA4
GJA8
GOLM1
GPR37L1
GPX8
GUCA2A
HIBADH
HSD17B13
IER3IP1
IFITM3
KIR2DL3
LAPTM4B
LIME1
LSS
LY6D
MARCHF2
MFF
MGST3
MMGT1
MS4A14
MSMO1
MUC1
NDUFAF1
NEMP1
NINJ2
ORMDL2
OTULINL
PEX11G
PGRMC2
PIGF
PLN
PSCA
PTPN1
PTPN9
RHBDD1
RHOT2
RPRM
RTP2
SEC22B
SERINC2
SFRP1
SFT2D1
SFXN5
SLC10A6
SLC29A2
SLC35G2
SLC39A9
SMIM1
SNORC
SSMEM1
STOM
STX12
STX6
STX8
TEX29
THAP4
THBD
TIMM23
TMEM106A
TMEM107
TMEM120A
TMEM14A
TMEM14C
TMEM203
TMEM237
TMEM248
TMEM52B
TMEM60
TMPRSS2
TMX2
TREX1
TSNARE1
USE1
VAMP2
VAMP3
VAMP5
VAPA
ZDHHC22
121 interacting genes:
ABL1
ACKR2
APOA2
APOD
APOL3
AQP4
ARL6IP6
ATP6V0B
C1GALT1
C2CD2L
C3orf52
CCDC167
CCL4
CD53
CIAO2A
CLDN19
CLDN4
CLEC1A
CLN6
COX20
CTXN3
CXCL16
CYBC1
CYP4F2
DEFB121
DOLK
ERMP1
FDFT1
FXYD6
GIMAP1
GIMAP5
GJB2
GPR108
GPR151
GPR61
GUCA2A
IGFBP5
INSIG2
ITGAM
KIR2DL3
LAPTM4B
LAT
LEPROTL1
LHFPL5
MAL
MALL
MARCHF2
MFSD11
MFSD6
MGST2
MIP
MS4A13
ORMDL2
OTOP2
P2RY13
PGAP2
PLN
PMP22
PNLIPRP1
PRAF2
PROKR2
PTPRN
QRFPR
REEP6
RNF152
RUSF1
RXFP4
S1PR5
SCARF1
SEC22B
SEC22C
SEC23A
SFTPC
SLC13A2
SLC13A5
SLC16A12
SLC16A13
SLC16A3
SLC30A3
SLC35A4
SLC35F1
SLC35F6
SLC38A4
SLC38A7
SLC39A2
SLC39A7
SLC39A9
SLC52A1
SLC66A1
SLC66A2
SLC8A3
SMCO4
SMIM1
STX1B
STX8
THSD7B
TJP1
TMBIM6
TMEM100
TMEM107
TMEM121
TMEM128
TMEM147
TMEM182
TMEM239
TMEM242
TMEM243
TMEM42
TMEM45A
TMEM60
TMEM65
TMEM72
TMEM86B
TSPAN33
TWSG1
UBXN8
UNC93A
UPK1B
VAMP5
YIF1A
YIPF6
Entrez ID
255043
2703
HPRD ID
14540
02939
Ensembl ID
ENSG00000180089
ENSG00000121634
Uniprot IDs
Q8N661
P48165
X5D7G1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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