TMEM86B and RHOT2

Data Source:
BioGRID (two hybrid)

		TMEM86B	RHOT2
Description		transmembrane protein 86B	ras homolog family member T2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Mitochondrion Cytosol Plasma Membrane Membrane Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	Protein Binding Ether Hydrolase Activity Identical Protein Binding Alkenylglycerophosphocholine Hydrolase Activity Alkenylglycerophosphoethanolamine Hydrolase Activity	GTPase Activity Calcium Ion Binding Protein Binding GTP Binding
	Biological Process	Phosphatidylcholine Acyl-chain Remodeling Ether Lipid Metabolic Process	Mitochondrion Organization Regulation Of Mitochondrion Organization Cellular Homeostasis Mitochondrion Transport Along Microtubule Regulation Of Small GTPase Mediated Signal Transduction Mitochondrial Outer Membrane Permeabilization
Pathways		Acyl chain remodelling of PC	Rho GTPase cycle
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Phosphatidylethanolamine-ether levels ( 31551469) Systemic lupus erythematosus ( 33536424 28714469)	Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Red blood cell traits ( 23446634)
Interacting Genes		105 interacting genes: AQP6 ARL13B ARL6IP6 ASGR2 BCL2L13 BIK BMP10 C2CD2L CCDC167 CCDC34 CCL4 CD53 CD79A CLRN1 CYB5B DHRSX DNAJC30 EBP ERGIC3 ERP29 EVI2B F11R FAM209A FAXDC2 FKBP7 FXYD6 GJA1 GJA4 GJA8 GOLM1 GPR37L1 GPX8 GUCA2A HIBADH HSD17B13 IER3IP1 IFITM3 KIR2DL3 LAPTM4B LIME1 LSS LY6D MARCHF2 MFF MGST3 MMGT1 MS4A14 MSMO1 MUC1 NDUFAF1 NEMP1 NINJ2 ORMDL2 OTULINL PEX11G PGRMC2 PIGF PLN PSCA PTPN1 PTPN9 RHBDD1 RHOT2 RPRM RTP2 SEC22B SERINC2 SFRP1 SFT2D1 SFXN5 SLC10A6 SLC29A2 SLC35G2 SLC39A9 SMIM1 SNORC SSMEM1 STOM STX12 STX6 STX8 TEX29 THAP4 THBD TIMM23 TMEM106A TMEM107 TMEM120A TMEM14A TMEM14C TMEM203 TMEM237 TMEM248 TMEM52B TMEM60 TMPRSS2 TMX2 TREX1 TSNARE1 USE1 VAMP2 VAMP3 VAMP5 VAPA ZDHHC22	5 interacting genes: PRKN SAR1A TMEM14B TMEM86B ZFYVE9
Entrez ID		255043	89941
HPRD ID		14540	15248
Ensembl ID		ENSG00000180089	ENSG00000140983
Uniprot IDs		Q8N661	Q8IXI1
PDB IDs			5KUT
Enriched GO Terms of Interacting Partners?
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