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TMEM86B and LAPTM4B
Data Source:
BioGRID
(two hybrid)
TMEM86B
LAPTM4B
Description
transmembrane protein 86B
lysosomal protein transmembrane 4 beta
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Lysosome
Lysosomal Membrane
Endosome
Early Endosome
Plasma Membrane
Integral Component Of Membrane
Late Endosome Membrane
Multivesicular Body Membrane
Cell Projection
Multivesicular Body, Internal Vesicle
Molecular Function
Protein Binding
Ether Hydrolase Activity
Identical Protein Binding
Alkenylglycerophosphocholine Hydrolase Activity
Alkenylglycerophosphoethanolamine Hydrolase Activity
Protein Binding
Kinase Binding
Ubiquitin Protein Ligase Binding
Ceramide Binding
Phosphatidylinositol Bisphosphate Binding
Biological Process
Phosphatidylcholine Acyl-chain Remodeling
Ether Lipid Metabolic Process
Endosome Organization
Endosome Transport Via Multivesicular Body Sorting Pathway
Negative Regulation Of Transforming Growth Factor Beta1 Production
Regulation Of Lysosomal Membrane Permeability
Negative Regulation Of Lysosomal Protein Catabolic Process
Regulation Of Lysosome Organization
Pathways
Acyl chain remodelling of PC
Drugs
Diseases
GWAS
Mean reticulocyte volume (
32888494
)
Phosphatidylethanolamine-ether levels (
31551469
)
Systemic lupus erythematosus (
33536424
28714469
)
Metabolite levels (
23823483
)
QT interval (
24952745
)
Interacting Genes
105 interacting genes:
AQP6
ARL13B
ARL6IP6
ASGR2
BCL2L13
BIK
BMP10
C2CD2L
CCDC167
CCDC34
CCL4
CD53
CD79A
CLRN1
CYB5B
DHRSX
DNAJC30
EBP
ERGIC3
ERP29
EVI2B
F11R
FAM209A
FAXDC2
FKBP7
FXYD6
GJA1
GJA4
GJA8
GOLM1
GPR37L1
GPX8
GUCA2A
HIBADH
HSD17B13
IER3IP1
IFITM3
KIR2DL3
LAPTM4B
LIME1
LSS
LY6D
MARCHF2
MFF
MGST3
MMGT1
MS4A14
MSMO1
MUC1
NDUFAF1
NEMP1
NINJ2
ORMDL2
OTULINL
PEX11G
PGRMC2
PIGF
PLN
PSCA
PTPN1
PTPN9
RHBDD1
RHOT2
RPRM
RTP2
SEC22B
SERINC2
SFRP1
SFT2D1
SFXN5
SLC10A6
SLC29A2
SLC35G2
SLC39A9
SMIM1
SNORC
SSMEM1
STOM
STX12
STX6
STX8
TEX29
THAP4
THBD
TIMM23
TMEM106A
TMEM107
TMEM120A
TMEM14A
TMEM14C
TMEM203
TMEM237
TMEM248
TMEM52B
TMEM60
TMPRSS2
TMX2
TREX1
TSNARE1
USE1
VAMP2
VAMP3
VAMP5
VAPA
ZDHHC22
21 interacting genes:
BDKRB1
CGRRF1
CTXN3
CYB561A3
EMP1
GJA8
GPX8
IFNAR1
IGFBP5
ISLR2
MTIF3
NAALADL2
NRG1
ODF4
PIP5K1C
SCARB2
SLC22A1
SLC22A2
SLC29A2
TMEM86B
TRARG1
Entrez ID
255043
55353
HPRD ID
14540
13960
Ensembl ID
ENSG00000180089
ENSG00000104341
Uniprot IDs
Q8N661
Q86VI4
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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