ATP6V0D2 and CRX

Data Source:
BioGRID (two hybrid)

		ATP6V0D2	CRX
Description		ATPase H+ transporting V0 subunit d2	cone-rod homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome	Chromatin Nucleus RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Activator Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Nuclear Hormone Receptor Binding Leucine Zipper Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Vacuolar Transport Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Nervous System Development Visual Perception Animal Organ Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Response To Stimulus
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases			Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)
Interacting Genes		20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474	112 interacting genes: AASDHPPT ABI2 ACBD4 ARIH2 ATG12 ATM ATP6V0D2 ATXN1 ATXN7 BANF1 BANF2 BANP BOD1L2 C19orf25 C1orf109 C1orf50 C1orf56 C9orf72 CA8 CCNC CDKN2C CFAP206 CREBBP CSNK1G2-AS1 CTNNA3 DELE1 EIF5A EP300 FAAP20 FOXH1 GCM2 GLIS2 GUCD1 GYS1 HGS HNF1B IGFN1 IPO13 IRX6 KANK2 KAT2A KLHL32 LARP4 LGALS3 LIMS3 LIMS4 LNX1 LONRF1 M1AP MDFI MLLT6 MYO15B MYOZ1 NEIL2 NFYC NIP7 NPAS2 NR2E3 NRL NTF4 OR6B1 OSGIN1 OSTF1 PDC PICALM PID1 PNMA6A POGZ PPP1R16B PRKAB2 PRKN PRR35 PSMA1 PSMB10 PSMF1 QRICH1 RAX2 RBFOX1 RBPMS RHOXF2 ROR2 SAE1 SDCBP SEC14L4 SFI1 SMAD3 SMAP1 SMAP2 SMUG1 SOX10 SOX14 SOX3 SOX5 SPG21 STK16 SUFU SUOX SZT2 TBX6 TCF7L2 TEX33 TFG TLE5 TLX3 TNS2 UBXN2B UBXN7 VPS37C ZC3H10 ZIC1 ZNF483 ZNF688
Entrez ID		245972	1406
HPRD ID		16522	03748
Ensembl ID		ENSG00000147614	ENSG00000105392
Uniprot IDs		A0A024R991 Q8N8Y2	O43186
PDB IDs
Enriched GO Terms of Interacting Partners?
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