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CRX and NIP7
Data Source:
BioGRID
(two hybrid)
CRX
NIP7
Description
cone-rod homeobox
nucleolar pre-rRNA processing protein NIP7
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
RNA Polymerase II Transcription Regulator Complex
Nucleoplasm
Nucleolus
Cytosol
Preribosome, Large Subunit Precursor
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Nuclear Hormone Receptor Binding
Leucine Zipper Domain Binding
Sequence-specific Double-stranded DNA Binding
RNA Binding
Protein Binding
Biological Process
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Visual Perception
Animal Organ Morphogenesis
Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Response To Stimulus
Ribosome Assembly
Ribosomal Large Subunit Biogenesis
Pathways
Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Radezolid
Diseases
Leber congenital amaurosis (LCR)
Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS
Body mass index (
26426971
)
Logical memory (delayed recall) in normal cognition (
29274321
)
Interacting Genes
112 interacting genes:
AASDHPPT
ABI2
ACBD4
ARIH2
ATG12
ATM
ATP6V0D2
ATXN1
ATXN7
BANF1
BANF2
BANP
BOD1L2
C19orf25
C1orf109
C1orf50
C1orf56
C9orf72
CA8
CCNC
CDKN2C
CFAP206
CREBBP
CSNK1G2-AS1
CTNNA3
DELE1
EIF5A
EP300
FAAP20
FOXH1
GCM2
GLIS2
GUCD1
GYS1
HGS
HNF1B
IGFN1
IPO13
IRX6
KANK2
KAT2A
KLHL32
LARP4
LGALS3
LIMS3
LIMS4
LNX1
LONRF1
M1AP
MDFI
MLLT6
MYO15B
MYOZ1
NEIL2
NFYC
NIP7
NPAS2
NR2E3
NRL
NTF4
OR6B1
OSGIN1
OSTF1
PDC
PICALM
PID1
PNMA6A
POGZ
PPP1R16B
PRKAB2
PRKN
PRR35
PSMA1
PSMB10
PSMF1
QRICH1
RAX2
RBFOX1
RBPMS
RHOXF2
ROR2
SAE1
SDCBP
SEC14L4
SFI1
SMAD3
SMAP1
SMAP2
SMUG1
SOX10
SOX14
SOX3
SOX5
SPG21
STK16
SUFU
SUOX
SZT2
TBX6
TCF7L2
TEX33
TFG
TLE5
TLX3
TNS2
UBXN2B
UBXN7
VPS37C
ZC3H10
ZIC1
ZNF483
ZNF688
5 interacting genes:
CRX
LZTS2
NECAB2
NOL8
ZBED1
Entrez ID
1406
51388
HPRD ID
03748
16709
Ensembl ID
ENSG00000105392
ENSG00000132603
Uniprot IDs
O43186
Q9Y221
PDB IDs
1SQW
1T5Y
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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