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CRX and LONRF1
Data Source:
BioGRID
(two hybrid, two hybrid)
CRX
LONRF1
Description
cone-rod homeobox
LON peptidase N-terminal domain and ring finger 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
RNA Polymerase II Transcription Regulator Complex
Cytosol
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Nuclear Hormone Receptor Binding
Leucine Zipper Domain Binding
Sequence-specific Double-stranded DNA Binding
Protein Binding
Metal Ion Binding
Biological Process
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Visual Perception
Animal Organ Morphogenesis
Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Response To Stimulus
Protein Polyubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
Leber congenital amaurosis (LCR)
Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS
Apolipoprotein A1 levels (
32203549
)
Colorectal cancer (diet interaction) (
24743840
)
HDL cholesterol levels (
32203549
)
Interacting Genes
112 interacting genes:
AASDHPPT
ABI2
ACBD4
ARIH2
ATG12
ATM
ATP6V0D2
ATXN1
ATXN7
BANF1
BANF2
BANP
BOD1L2
C19orf25
C1orf109
C1orf50
C1orf56
C9orf72
CA8
CCNC
CDKN2C
CFAP206
CREBBP
CSNK1G2-AS1
CTNNA3
DELE1
EIF5A
EP300
FAAP20
FOXH1
GCM2
GLIS2
GUCD1
GYS1
HGS
HNF1B
IGFN1
IPO13
IRX6
KANK2
KAT2A
KLHL32
LARP4
LGALS3
LIMS3
LIMS4
LNX1
LONRF1
M1AP
MDFI
MLLT6
MYO15B
MYOZ1
NEIL2
NFYC
NIP7
NPAS2
NR2E3
NRL
NTF4
OR6B1
OSGIN1
OSTF1
PDC
PICALM
PID1
PNMA6A
POGZ
PPP1R16B
PRKAB2
PRKN
PRR35
PSMA1
PSMB10
PSMF1
QRICH1
RAX2
RBFOX1
RBPMS
RHOXF2
ROR2
SAE1
SDCBP
SEC14L4
SFI1
SMAD3
SMAP1
SMAP2
SMUG1
SOX10
SOX14
SOX3
SOX5
SPG21
STK16
SUFU
SUOX
SZT2
TBX6
TCF7L2
TEX33
TFG
TLE5
TLX3
TNS2
UBXN2B
UBXN7
VPS37C
ZC3H10
ZIC1
ZNF483
ZNF688
96 interacting genes:
ADAMTSL4
ALAS1
AP2B1
ATG9A
AVPI1
BHLHB9
BRCA1
BYSL
C4orf17
CALCOCO2
CBLL2
CDKN2D
CFP
CRX
CYSRT1
DVL3
EFHC2
FLACC1
GABPB2
GORASP1
GORASP2
HLX
HOXA1
HSPB1
IHO1
IKZF2
IKZF3
IQCF2
KAT5
KATNBL1
KCTD21
KCTD9
KHDC1
KRT31
KRT35
KRT75
KRTAP1-3
KRTAP13-1
KRTAP13-3
KRTAP19-6
KRTAP19-7
KRTAP3-3
KRTAP6-1
LGALS9B
LHX2
LHX4
LNX1
MAGED1
MGAT5B
MID2
MRPL38
MTMR3
MYOZ3
NR4A1
NTAQ1
OOEP
PATZ1
PAX5
PAX6
PAX8
PICK1
PLSCR1
POU6F2
PPP1R3C
PRDM16
PRDM6
PRR35
PSMA1
RBPMS
RIMBP3C
RPRD1A
SFN
SLU7
SPRY2
STAU1
STX11
TASOR2
TBX19
TRAF2
TRIM27
TRIM42
TRIM8
TRIM9
UBE2I
UBE2L6
UCHL3
USP2
VGLL1
WDR83
XIAP
YPEL3
ZFP90
ZNF426
ZNF653
ZNF774
ZNHIT2
Entrez ID
1406
91694
HPRD ID
03748
08674
Ensembl ID
ENSG00000105392
ENSG00000154359
Uniprot IDs
O43186
Q17RB8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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