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CRX and FOXH1
Data Source:
BioGRID
(two hybrid)
CRX
FOXH1
Description
cone-rod homeobox
forkhead box H1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
RNA Polymerase II Transcription Regulator Complex
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Activin Responsive Factor Complex
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Transcription Factor Binding
DNA-binding Transcription Activator Activity
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Nuclear Hormone Receptor Binding
Leucine Zipper Domain Binding
Sequence-specific Double-stranded DNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Protein Domain Specific Binding
BHLH Transcription Factor Binding
Sequence-specific DNA Binding
SMAD Binding
Androgen Receptor Binding
Co-SMAD Binding
R-SMAD Binding
Biological Process
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Visual Perception
Animal Organ Morphogenesis
Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Response To Stimulus
Negative Regulation Of Transcription By RNA Polymerase II
Heart Looping
Secondary Heart Field Specification
Outflow Tract Morphogenesis
Cardiac Right Ventricle Morphogenesis
Ventricular Trabecula Myocardium Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Embryonic Heart Tube Anterior/posterior Pattern Specification
Aorta Morphogenesis
Negative Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Axial Mesoderm Development
Negative Regulation Of Androgen Receptor Signaling Pathway
Cellular Response To Cytokine Stimulus
Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Pathways
Signaling by NODAL
Signaling by Activin
Drugs
Diseases
Leber congenital amaurosis (LCR)
Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS
Blood metabolite levels (
26401656
)
Educational attainment (
25201988
)
General cognitive ability (
29844566
)
Interacting Genes
112 interacting genes:
AASDHPPT
ABI2
ACBD4
ARIH2
ATG12
ATM
ATP6V0D2
ATXN1
ATXN7
BANF1
BANF2
BANP
BOD1L2
C19orf25
C1orf109
C1orf50
C1orf56
C9orf72
CA8
CCNC
CDKN2C
CFAP206
CREBBP
CSNK1G2-AS1
CTNNA3
DELE1
EIF5A
EP300
FAAP20
FOXH1
GCM2
GLIS2
GUCD1
GYS1
HGS
HNF1B
IGFN1
IPO13
IRX6
KANK2
KAT2A
KLHL32
LARP4
LGALS3
LIMS3
LIMS4
LNX1
LONRF1
M1AP
MDFI
MLLT6
MYO15B
MYOZ1
NEIL2
NFYC
NIP7
NPAS2
NR2E3
NRL
NTF4
OR6B1
OSGIN1
OSTF1
PDC
PICALM
PID1
PNMA6A
POGZ
PPP1R16B
PRKAB2
PRKN
PRR35
PSMA1
PSMB10
PSMF1
QRICH1
RAX2
RBFOX1
RBPMS
RHOXF2
ROR2
SAE1
SDCBP
SEC14L4
SFI1
SMAD3
SMAP1
SMAP2
SMUG1
SOX10
SOX14
SOX3
SOX5
SPG21
STK16
SUFU
SUOX
SZT2
TBX6
TCF7L2
TEX33
TFG
TLE5
TLX3
TNS2
UBXN2B
UBXN7
VPS37C
ZC3H10
ZIC1
ZNF483
ZNF688
67 interacting genes:
AOC1
ARID5A
ATP23
ATXN1L
BATF2
C10orf55
C11orf1
C19orf54
CEACAM6
CRX
CRYBA1
CYSRT1
DAZAP2
DRAP1
FAM168B
FAM83A
FOXD2
FOXG1
HDHD3
HEY1
HLX
HOXA1
HSF4
KLHL26
KRTAP11-1
KRTAP13-3
KRTAP19-2
KRTAP19-6
KRTAP19-7
KRTAP3-1
KRTAP3-3
KRTAP7-1
LASP1
MAGED1
MGAT5B
MSX2
NKX2-5
NOTO
OXER1
PLA2G10
PNMA5
PPP1R37
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR22
RBM46
RBPMS2
RNF144B
SERGEF
SMAD2
SMAD3
SMAD4
SOX14
SOX4
TEKT5
TFG
TLX3
TSC1
UBAP2
UFSP1
ZC3H10
ZIC1
ZNF34
ZNF503
Entrez ID
1406
8928
HPRD ID
03748
04689
Ensembl ID
ENSG00000105392
ENSG00000160973
Uniprot IDs
O43186
O75593
PDB IDs
5XOC
Enriched GO Terms of Interacting Partners
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