CRX and C1orf109

Data Source:
BioGRID (two hybrid)

		CRX	C1orf109
Description		cone-rod homeobox	chromosome 1 open reading frame 109
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus RNA Polymerase II Transcription Regulator Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Activator Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Nuclear Hormone Receptor Binding Leucine Zipper Domain Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Nervous System Development Visual Perception Animal Organ Morphogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Response To Stimulus
Pathways
Drugs
Diseases		Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS			Axial length ( 24144296) Eyebrow thickness ( 26926045)
Interacting Genes		112 interacting genes: AASDHPPT ABI2 ACBD4 ARIH2 ATG12 ATM ATP6V0D2 ATXN1 ATXN7 BANF1 BANF2 BANP BOD1L2 C19orf25 C1orf109 C1orf50 C1orf56 C9orf72 CA8 CCNC CDKN2C CFAP206 CREBBP CSNK1G2-AS1 CTNNA3 DELE1 EIF5A EP300 FAAP20 FOXH1 GCM2 GLIS2 GUCD1 GYS1 HGS HNF1B IGFN1 IPO13 IRX6 KANK2 KAT2A KLHL32 LARP4 LGALS3 LIMS3 LIMS4 LNX1 LONRF1 M1AP MDFI MLLT6 MYO15B MYOZ1 NEIL2 NFYC NIP7 NPAS2 NR2E3 NRL NTF4 OR6B1 OSGIN1 OSTF1 PDC PICALM PID1 PNMA6A POGZ PPP1R16B PRKAB2 PRKN PRR35 PSMA1 PSMB10 PSMF1 QRICH1 RAX2 RBFOX1 RBPMS RHOXF2 ROR2 SAE1 SDCBP SEC14L4 SFI1 SMAD3 SMAP1 SMAP2 SMUG1 SOX10 SOX14 SOX3 SOX5 SPG21 STK16 SUFU SUOX SZT2 TBX6 TCF7L2 TEX33 TFG TLE5 TLX3 TNS2 UBXN2B UBXN7 VPS37C ZC3H10 ZIC1 ZNF483 ZNF688	144 interacting genes: ABI2 ADD1 ANTKMT ATP23 AVPI1 BORCS6 C1orf94 C1QTNF2 C9orf24 CBY2 CCDC120 CCDC125 CCDC33 CCDC88B CCHCR1 CDCA4 CEP55 CINP CRX CSNK2A1 CT55 CTAG1A CTAG1B DISC1 ECM1 ECSIT FAM217B FAM86C1P FTO GET4 GIGYF1 GOLGA2 GOLGA6A GOLGA6L9 HESX1 HOOK2 HOXC8 IHO1 IKZF1 IKZF3 INKA1 KATNAL1 KIAA0753 KIFC3 KLF15 KRT13 KRT16 KRT18 KRT19 KRT24 KRT31 KRT35 KRT40 KRT75 KRT76 KRT80 KRTAP13-3 LDOC1 LMO2 LZTS2 MBD3L1 MDM4 MEI4 MEOX1 MEOX2 MIPOL1 MKRN2 MTFR1L MTUS2 NDUFB7 NECAB2 NFKBID NME4 NUP54 NUTM2F OOEP PAX5 PAX6 PAX7 PBX4 PDE4DIP PHC2 PLK4 PNMA1 POMC POU6F2 PPP1R12C PRDM6 PRMT5 PSMB4 PUDP REL RINT1 RNF20 RNF41 RPH3AL RUSC1 SAPCD2 SDCBP SERTAD1 SERTAD2 SLAIN1 SMARCD1 SOCS6 SORBS3 SPAG5 STMN3 STN1 STX11 TADA2A TASOR2 TCF12 TCF4 TEKT4 TEPSIN TFIP11 TLE5 TNNI2 TRAF1 TRIM27 TRIM42 TRIM54 TSGA10IP TTC12 TTC23 TTC23L UHMK1 USH1G USHBP1 VBP1 VGLL1 VPS52 YPEL3 ZBED1 ZBTB42 ZMAT1 ZMAT5 ZMYND12 ZNF17 ZNF20 ZNF398 ZNF420 ZNF688 ZSCAN9
Entrez ID		1406	54955
HPRD ID		03748	07918
Ensembl ID		ENSG00000105392	ENSG00000116922
Uniprot IDs		O43186	B4DRQ5 B7Z9X8 Q9NX04
PDB IDs
Enriched GO Terms of Interacting Partners?
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