SCFD1 and USP22

Data Source:
BioGRID (two hybrid)

		SCFD1	USP22
Description		sec1 family domain containing 1	ubiquitin specific peptidase 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi-associated Vesicle Cis-Golgi Network Cytosol Plasma Membrane Golgi Cisterna Membrane	SAGA Complex Nucleoplasm SAGA-type Complex
	Molecular Function	Protein Binding Syntaxin Binding Protein-containing Complex Binding Protein N-terminus Binding	Transcription Coactivator Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Zinc Ion Binding H4 Histone Acetyltransferase Activity Enzyme Binding Nuclear Receptor Coactivator Activity
	Biological Process	Cell Morphogenesis Response To Hypoxia Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Post-Golgi Vesicle-mediated Transport Vesicle Docking Involved In Exocytosis Response To Toxic Substance Vesicle-mediated Transport COPII Vesicle Coating Regulation Of Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Toxin Transport Negative Regulation Of Autophagosome Assembly	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Embryo Development Ending In Birth Or Egg Hatching Histone Ubiquitination Histone Deubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle
Pathways		COPII-mediated vesicle transport	HATs acetylate histones Ub-specific processing proteases
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 29566793 27455348) Cognitive decline (age-related) ( 28078323) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Body mass index ( 26426971) Mosquito bite size ( 28199695)
Interacting Genes		5 interacting genes: DLST PPBP STX5 USO1 USP22	17 interacting genes: AASDHPPT ATXN7 ATXN7L3 BAG4 CD274 H2AC20 H2BC21 HEXA MRPL10 MRPL44 MTUS2 MYC PSME1 PTGS2 RCAN1 SCFD1 UBC
Entrez ID		23256	23326
HPRD ID		10210	19411
Ensembl ID		ENSG00000092108	ENSG00000124422
Uniprot IDs		B7Z5N7 B7Z738 Q8WVM8	Q9UPT9
PDB IDs
Enriched GO Terms of Interacting Partners?
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