USP22 and MRPL44

Data Source:
BioGRID (two hybrid)

		USP22	MRPL44
Description		ubiquitin specific peptidase 22	mitochondrial ribosomal protein L44
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleoplasm SAGA-type Complex	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Plasma Membrane Nuclear Body
	Molecular Function	Transcription Coactivator Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Zinc Ion Binding H4 Histone Acetyltransferase Activity Enzyme Binding Nuclear Receptor Coactivator Activity	RNA Binding Double-stranded RNA Binding Ribonuclease III Activity Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Embryo Development Ending In Birth Or Egg Hatching Histone Ubiquitination Histone Deubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle	RNA Processing Production Of SiRNA Involved In RNA Interference Primary MiRNA Processing Pre-miRNA Processing Mitochondrial Translational Elongation Mitochondrial Translational Termination RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		HATs acetylate histones Ub-specific processing proteases	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mosquito bite size ( 28199695)
Interacting Genes		17 interacting genes: AASDHPPT ATXN7 ATXN7L3 BAG4 CD274 H2AC20 H2BC21 HEXA MRPL10 MRPL44 MTUS2 MYC PSME1 PTGS2 RCAN1 SCFD1 UBC	15 interacting genes: ABI2 CEP70 DGKE IMMT ITFG1 NGEF PI4KA PLPP2 PTN SEMA5B SETDB1 SHC1 USP22 VIM ZNF235
Entrez ID		23326	65080
HPRD ID		19411	14763
Ensembl ID		ENSG00000124422	ENSG00000135900
Uniprot IDs		Q9UPT9	A1MA90 Q9H9J2
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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