SCFD1 and STX5

Data Source:
HPRD (in vitro)

		SCFD1	STX5
Description		sec1 family domain containing 1	syntaxin 5
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi-associated Vesicle Cis-Golgi Network Cytosol Plasma Membrane Golgi Cisterna Membrane	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Syntaxin Binding Protein-containing Complex Binding Protein N-terminus Binding	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding Protein N-terminus Binding
	Biological Process	Cell Morphogenesis Response To Hypoxia Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Post-Golgi Vesicle-mediated Transport Vesicle Docking Involved In Exocytosis Response To Toxic Substance Vesicle-mediated Transport COPII Vesicle Coating Regulation Of Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Toxin Transport Negative Regulation Of Autophagosome Assembly	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization
Pathways		COPII-mediated vesicle transport	COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 29566793 27455348) Cognitive decline (age-related) ( 28078323) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: DLST PPBP STX5 USO1 USP22	52 interacting genes: AARD APLP1 AQP6 BAG6 BET1 CCDC153 COPS6 CRB3 CREB3L3 EBP FAM209A GET3 GOSR1 GOSR2 GPANK1 GPR152 HAP1 HSD17B11 HSD17B13 IMMT JAGN1 KASH5 LMNA LNX1 LRIF1 LRRC4C MAGEA6 MTUS1 NAPA NAPB NSFL1C REEP4 RETREG3 SCFD1 SEC22B SNAP23 SNAP25 STING1 STX1A STX2 STX3 STX4 STX8 STXBP1 TACC1 TMEM31 TP53 USO1 VAMP5 VAPB VCP VCPIP1
Entrez ID		23256	6811
HPRD ID		10210	04426
Ensembl ID		ENSG00000092108	ENSG00000162236
Uniprot IDs		B7Z5N7 B7Z738 Q8WVM8	B4DKR0 Q13190
PDB IDs			3EFO
Enriched GO Terms of Interacting Partners?
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