USP22 and MRPL10

Data Source:
BioGRID (two hybrid)

		USP22	MRPL10
Description		ubiquitin specific peptidase 22	mitochondrial ribosomal protein L10
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleoplasm SAGA-type Complex	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Large Ribosomal Subunit Ribonucleoprotein Complex
	Molecular Function	Transcription Coactivator Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Zinc Ion Binding H4 Histone Acetyltransferase Activity Enzyme Binding Nuclear Receptor Coactivator Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Embryo Development Ending In Birth Or Egg Hatching Histone Ubiquitination Histone Deubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle	Translation Ribosome Biogenesis Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		HATs acetylate histones Ub-specific processing proteases	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mosquito bite size ( 28199695)	Alzheimer's disease (cognitive decline) ( 23535033) Asthma ( 31619474) Body mass index ( 26426971)
Interacting Genes		17 interacting genes: AASDHPPT ATXN7 ATXN7L3 BAG4 CD274 H2AC20 H2BC21 HEXA MRPL10 MRPL44 MTUS2 MYC PSME1 PTGS2 RCAN1 SCFD1 UBC	8 interacting genes: ACTN2 APP FAM9B KLHL12 PNMA1 REL TCF4 USP22
Entrez ID		23326	124995
HPRD ID		19411	14738
Ensembl ID		ENSG00000124422	ENSG00000159111
Uniprot IDs		Q9UPT9	Q7Z7H8
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG
Enriched GO Terms of Interacting Partners?
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