SCFD1 and PPBP

Data Source:
HPRD (two hybrid)

		SCFD1	PPBP
Description		sec1 family domain containing 1	pro-platelet basic protein
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi-associated Vesicle Cis-Golgi Network Cytosol Plasma Membrane Golgi Cisterna Membrane	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Tertiary Granule Lumen
	Molecular Function	Protein Binding Syntaxin Binding Protein-containing Complex Binding Protein N-terminus Binding	Glucose Transmembrane Transporter Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding
	Biological Process	Cell Morphogenesis Response To Hypoxia Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Post-Golgi Vesicle-mediated Transport Vesicle Docking Involved In Exocytosis Response To Toxic Substance Vesicle-mediated Transport COPII Vesicle Coating Regulation Of Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Toxin Transport Negative Regulation Of Autophagosome Assembly	Platelet Degranulation Inflammatory Response G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Glucose Transmembrane Transport
Pathways		COPII-mediated vesicle transport	Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs			Ethanesulfonic acid Copper
Diseases
GWAS		Amyotrophic lateral sclerosis ( 29566793 27455348) Cognitive decline (age-related) ( 28078323) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Metabolite levels ( 22916037)
Interacting Genes		5 interacting genes: DLST PPBP STX5 USO1 USP22	32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 CXCL9 CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4
Entrez ID		23256	5473
HPRD ID		10210	07171
Ensembl ID		ENSG00000092108	ENSG00000163736
Uniprot IDs		B7Z5N7 B7Z738 Q8WVM8	P02775
PDB IDs			1F9P 1NAP 1TVX
Enriched GO Terms of Interacting Partners?
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