DIP2A and JMJD6

Data Source:
BioGRID (two hybrid)

		DIP2A	JMJD6
Description		disco interacting protein 2 homolog A	jumonji domain containing 6, arginine demethylase and lysine hydroxylase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Cell Surface Membrane Dendritic Spine	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Ribonucleoprotein Complex
	Molecular Function	Acetate-CoA Ligase Activity Protein Binding	RNA Binding Single-stranded RNA Binding Iron Ion Binding Protein Binding Demethylase Activity Histone Demethylase Activity Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Oxidative RNA Demethylase Activity Signaling Receptor Activity Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity P-TEFb Complex Binding Transcription Regulator Activator Activity
	Biological Process	Acetyl-CoA Biosynthetic Process Negative Regulation Of Gene Expression Dendritic Spine Morphogenesis Positive Regulation Of Peptidyl-lysine Acetylation	Kidney Development Sprouting Angiogenesis MRNA Processing Protein Demethylation Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Protein Phosphopantetheinylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Oxidative RNA Demethylation Macrophage Activation Recognition Of Apoptotic Cell Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Protein Homooligomerization Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation
Pathways			HDMs demethylate histones
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Lymphocyte counts ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Neutrophil count ( 32888494) Pulse pressure ( 30224653) White blood cell count ( 32888494)	Neutrophil count ( 32888494) Retinal arteriolar caliber ( 23776548)
Interacting Genes		19 interacting genes: ADAMTSL4 CCDC33 CEP44 DAB2 DLX2 FAM214B GPATCH2L IQUB JMJD6 MBIP PSME3 PTPN3 SORBS3 STAC3 TLE5 TMCC2 TRIM39 TRIP13 ZBTB43	27 interacting genes: AEBP2 ANKEF1 C17orf97 CCNL1 CENPL CXCL14 DIP2A FGD5 FRMD6 GNA14 H2BC11 H3C1 H4C1 HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZNF451
Entrez ID		23181	23210
HPRD ID		07611	05371
Ensembl ID		ENSG00000160305	ENSG00000070495
Uniprot IDs		Q14689 Q96NX2	Q6NYC1
PDB IDs			3K2O 3LD8 3LDB 6BNH 6GDY 6MEV
Enriched GO Terms of Interacting Partners?
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