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CHMP2A and USP8
Data Source:
BioGRID
(pull down)
CHMP2A
USP8
Description
charged multivesicular body protein 2A
ubiquitin specific peptidase 8
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
ESCRT III Complex
Nuclear Envelope
Multivesicular Body
Cytosol
Membrane
Membrane Coat
Late Endosome Membrane
Extracellular Exosome
Nucleus
Cytoplasm
Early Endosome
Cytosol
Postsynaptic Density
Extrinsic Component Of Plasma Membrane
Midbody
Extrinsic Component Of Endosome Membrane
Dendritic Spine
Glutamatergic Synapse
Molecular Function
Protein Binding
Protein Domain Specific Binding
Phosphatidylcholine Binding
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
SH3 Domain Binding
Cadherin Binding
Biological Process
Nucleus Organization
Mitotic Metaphase Plate Congression
Membrane Invagination
Exit From Mitosis
Regulation Of Centrosome Duplication
Protein Transport
Endosomal Transport
Macroautophagy
Viral Life Cycle
Nuclear Envelope Reassembly
Endosome Transport Via Multivesicular Body Sorting Pathway
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Establishment Of Protein Localization
Late Endosome To Vacuole Transport
Regulation Of Viral Process
Protein Polymerization
Protein Homooligomerization
Negative Regulation Of Cell Death
Midbody Abscission
Regulation Of Mitotic Spindle Assembly
Positive Regulation Of Viral Release From Host Cell
Positive Regulation Of Exosomal Secretion
Negative Regulation Of Centriole Elongation
ESCRT III Complex Disassembly
Mitotic Cytokinesis
Ubiquitin-dependent Protein Catabolic Process
Endosome Organization
Ras Protein Signal Transduction
Protein Deubiquitination
Protein Phosphopantetheinylation
Regulation Of Protein Stability
Regulation Of Protein Localization
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
Cellular Response To Dexamethasone Stimulus
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission
Cellular Response To Nerve Growth Factor Stimulus
Pathways
Budding and maturation of HIV virion
Macroautophagy
Lysosome Vesicle Biogenesis
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Sealing of the nuclear envelope (NE) by ESCRT-III
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
Downregulation of ERBB2:ERBB3 signaling
Regulation of FZD by ubiquitination
Ub-specific processing proteases
Negative regulation of MET activity
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Ankylosing spondylitis (
30946743
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Heel bone mineral density (
30598549
)
Mean reticulocyte volume (
32888494
)
Monocyte percentage of white cells (
32888494
)
Interacting Genes
13 interacting genes:
CHMP3
DOCK8
E2F4
EIF2B5
MITD1
NOL4
STAMBP
TGFB3
UFD1
USP54
USP8
VPS4A
VPS4B
40 interacting genes:
BACE1
BIRC6
CFLAR
CHMP1A
CHMP1B
CHMP2A
CHMP2B
CHMP4C
CHMP7
DNAJB6
EPS15
GRAP2
GRB2
H2AC20
H2BC21
KIF23
NBR1
PJA1
PLA2G2A
RASGRF1
RNF41
SEC31A
SHANK1
SHANK3
SLBP
SNCA
SPP1
SRC
STAM
STAM2
TRIM54
TRIM55
TRIM63
UBC
USP15
USP21
USP28
YWHAG
YWHAQ
YWHAZ
Entrez ID
27243
9101
HPRD ID
12520
04405
Ensembl ID
ENSG00000130724
ENSG00000138592
Uniprot IDs
A0A024R4S0
O43633
A0A024R5S4
A8K8N5
P40818
PDB IDs
1WHB
2A9U
2GFO
2GWF
3N3K
6F09
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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