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C1orf109 and TRAF1
Data Source:
BioGRID
(two hybrid, two hybrid)
C1orf109
TRAF1
Description
chromosome 1 open reading frame 109
TNF receptor associated factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Cytoplasm
Cytosol
Cytoplasmic Side Of Plasma Membrane
Plasma Membrane Signaling Receptor Complex
Molecular Function
Protein Binding
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Identical Protein Binding
Biological Process
Apoptotic Process
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of JNK Cascade
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein-containing Complex Assembly
Protein K63-linked Ubiquitination
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Drugs
Diseases
GWAS
Axial length (
24144296
)
Eyebrow thickness (
26926045
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Asthma (
32296059
)
Celiac disease or Rheumatoid arthritis (
21383967
)
Eosinophil percentage of white cells (
32888494
)
Lymphocyte counts (
32888494
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Monocyte count (
32888494
)
Pulse pressure (
30578418
)
Refractive error (
32231278
)
Rheumatoid arthritis (
30891314
24782177
23143596
24390342
20453842
19503088
)
Rheumatoid arthritis (ACPA-positive) (
23143596
24532676
)
White blood cell count (
32888494
)
Interacting Genes
144 interacting genes:
ABI2
ADD1
ANTKMT
ATP23
AVPI1
BORCS6
C1orf94
C1QTNF2
C9orf24
CBY2
CCDC120
CCDC125
CCDC33
CCDC88B
CCHCR1
CDCA4
CEP55
CINP
CRX
CSNK2A1
CT55
CTAG1A
CTAG1B
DISC1
ECM1
ECSIT
FAM217B
FAM86C1P
FTO
GET4
GIGYF1
GOLGA2
GOLGA6A
GOLGA6L9
HESX1
HOOK2
HOXC8
IHO1
IKZF1
IKZF3
INKA1
KATNAL1
KIAA0753
KIFC3
KLF15
KRT13
KRT16
KRT18
KRT19
KRT24
KRT31
KRT35
KRT40
KRT75
KRT76
KRT80
KRTAP13-3
LDOC1
LMO2
LZTS2
MBD3L1
MDM4
MEI4
MEOX1
MEOX2
MIPOL1
MKRN2
MTFR1L
MTUS2
NDUFB7
NECAB2
NFKBID
NME4
NUP54
NUTM2F
OOEP
PAX5
PAX6
PAX7
PBX4
PDE4DIP
PHC2
PLK4
PNMA1
POMC
POU6F2
PPP1R12C
PRDM6
PRMT5
PSMB4
PUDP
REL
RINT1
RNF20
RNF41
RPH3AL
RUSC1
SAPCD2
SDCBP
SERTAD1
SERTAD2
SLAIN1
SMARCD1
SOCS6
SORBS3
SPAG5
STMN3
STN1
STX11
TADA2A
TASOR2
TCF12
TCF4
TEKT4
TEPSIN
TFIP11
TLE5
TNNI2
TRAF1
TRIM27
TRIM42
TRIM54
TSGA10IP
TTC12
TTC23
TTC23L
UHMK1
USH1G
USHBP1
VBP1
VGLL1
VPS52
YPEL3
ZBED1
ZBTB42
ZMAT1
ZMAT5
ZMYND12
ZNF17
ZNF20
ZNF398
ZNF420
ZNF688
ZSCAN9
245 interacting genes:
A1CF
ABHD17A
ACTN3
AKAP17A
AQP1
ARID5A
ARNT2
ARSJ
BARD1
BCAS2
BCL6
BEX2
BEX3
BIRC2
BIRC3
C1orf109
C1orf216
C2CD6
C4orf45
CARHSP1
CASP10
CASP3
CASP6
CASP8
CCDC116
CCDC120
CCDC146
CCDC185
CCDC187
CCDC198
CCHCR1
CD40
CDCA3
CDK18
CDKN1A
CDKN2B
CFLAR
CHCHD3
COX5B
CRACR2A
CRY2
CRYGA
CYB5R2
DEPTOR
DGCR6
DMRT3
DOK3
DUSP13
DUSP21
DUSP4
EBF2
EDAR
EHHADH
ENKD1
EWSR1
FAM161A
FAM161B
FAM86C1P
FBF1
FBXL18
FOSL2
GADD45GIP1
GATA1
GATA2
GATAD2B
GCA
GCM2
GEM
GFI1B
GIT2
GLIS3
GLRX3
GMCL2
GNG5
GOLGA2
GORASP2
GRAP2
HAUS1
HELT
HEY2
HGS
HIVEP3
HMG20B
HNRNPM
HOXA1
HOXB5
HOXC8
HOXD12
IKBKB
JOSD1
KANK2
KIAA1217
KIF1A
KLHL38
KPNA2
KRT3
KRT75
LATS1
LCOR
LIN37
LMNTD2
LNX1
LNX2
LRRN1
LTBR
MACIR
MAP3K14
MAP6
MAPRE2
MATR3
METTL17
MORN3
MOS
MSGN1
MYEF2
MYOZ1
NEBL
NOL4L-DT
NTAQ1
NUFIP2
NUP58
OLIG3
PATZ1
PBX3
PDE4D
PHF21A
PIN1
PITX1
PITX2
PKN1
PLAC8
PLEKHN1
POM121L4P
POP5
PPP1R13B
PPP1R32
PRDM7
PRKAB2
PSMA1
PSMB1
QRICH1
RASAL2
RASSF5
RBCK1
RBM41
RBM45
RCOR3
RIIAD1
RIPK1
RIPK2
RIPOR3
RIPPLY1
RNF31
RTP5
SAMD11
SCNM1
SDCBP2
SH3GLB2
SHARPIN
SHC3
SHFL
SIK3
SLC25A48
SLC25A6
SNRNP25
SNW1
SOHLH1
SPATA46
SPG21
SPOP
SRC
SSC5D
STK3
SUMO2
SYCE1
TANK
TBC1D16
TBC1D8
TBX18
TCEA2
TCF7L2
TCL1A
TEAD4
TFAP2D
TFAP4
TFPT
THAP7
TICAM1
TIFA
TLE5
TNFAIP3
TNFRSF11A
TNFRSF12A
TNFRSF14
TNFRSF17
TNFRSF18
TNFRSF19
TNFRSF1A
TNFRSF1B
TNFRSF4
TNFRSF8
TNFRSF9
TNFSF9
TRADD
TRAF2
TRAF3IP2
TRAF6
TRAIP
TRIM23
TRIM37
TRIM42
TRPV6
TSHZ2
TSSC4
USP2
USP7
UTP14C
VEZF1
WAC
ZBTB1
ZBTB16
ZC2HC1C
ZFYVE21
ZFYVE26
ZIC1
ZNF124
ZNF20
ZNF23
ZNF250
ZNF417
ZNF440
ZNF490
ZNF502
ZNF512B
ZNF564
ZNF572
ZNF581
ZNF587
ZNF627
ZNF648
ZNF662
ZNF669
ZNF688
ZNF697
ZNF844
Entrez ID
54955
7185
HPRD ID
07918
03418
Ensembl ID
ENSG00000116922
ENSG00000056558
Uniprot IDs
B4DRQ5
B7Z9X8
Q9NX04
Q13077
PDB IDs
3M0D
5E1T
5H10
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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