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CHMP4B and EXOSC9
Data Source:
HPRD
(two hybrid)
CHMP4B
EXOSC9
Description
charged multivesicular body protein 4B
exosome component 9
Image
GO Annotations
Cellular Component
ESCRT III Complex
Nucleus
Nuclear Envelope
Cytoplasm
Endosome
Multivesicular Body
Cytosol
Cytoplasmic Side Of Plasma Membrane
Membrane Coat
Midbody
Late Endosome Membrane
Vesicle
Extracellular Exosome
Nuclear Exosome (RNase Complex)
Cytoplasmic Exosome (RNase Complex)
Exosome (RNase Complex)
Nuclear Chromosome
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Extracellular Exosome
Molecular Function
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Cadherin Binding
3'-5'-exoribonuclease Activity
RNA Polymerase II Activating Transcription Factor Binding
RNA Binding
Exoribonuclease Activity
Protein Binding
MRNA 3'-UTR AU-rich Region Binding
Biological Process
Mitotic Cytokinesis
Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane
Vesicle Budding From Membrane
Autophagy
Nucleus Organization
Mitotic Metaphase Plate Congression
Exit From Mitosis
Regulation Of Centrosome Duplication
Endosomal Transport
Macroautophagy
Viral Life Cycle
Nuclear Envelope Reassembly
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Multivesicular Body Assembly
Maintenance Of Lens Transparency
Viral Budding Via Host ESCRT Complex
Viral Budding
Regulation Of Viral Process
Protein Polymerization
Negative Regulation Of Cell Death
Midbody Abscission
Membrane Fission
Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Negative Regulation Of Neuron Death
Regulation Of Mitotic Spindle Assembly
Positive Regulation Of Viral Release From Host Cell
Negative Regulation Of Autophagosome Assembly
Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Nuclear-transcribed MRNA Catabolic Process
RRNA Processing
Immune Response
RRNA Catabolic Process
Positive Regulation Of Cell Growth
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5'
U1 SnRNA 3'-end Processing
U4 SnRNA 3'-end Processing
U5 SnRNA 3'-end Processing
Regulation Of MRNA Stability
Exonucleolytic Catabolism Of Deadenylated MRNA
Positive Regulation Of Transcription By RNA Polymerase II
Nuclear MRNA Surveillance
Nuclear Polyadenylation-dependent RRNA Catabolic Process
Nuclear Polyadenylation-dependent TRNA Catabolic Process
Nuclear Polyadenylation-dependent MRNA Catabolic Process
Pathways
Budding and maturation of HIV virion
Macroautophagy
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Sealing of the nuclear envelope (NE) by ESCRT-III
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
ATF4 activates genes in response to endoplasmic reticulum stress
mRNA decay by 3' to 5' exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
Feeling nervous (
29500382
)
Loneliness (
27629369
)
Offspring birth weight (
31043758
)
Refractive error (
32231278
)
Stearic acid (18:0) levels (
23362303
)
Mean corpuscular hemoglobin (
27863252
)
Mean corpuscular volume (
27863252
)
Red blood cell count (
32888494
)
Interacting Genes
16 interacting genes:
CHMP1B
CHMP3
CHMP4A
CHMP4C
CHMP5
CHMP6
EXOSC9
HIPK2
NOD2
PDCD6IP
PIAS2
PLIN3
PTPN23
STAMBP
UBE2I
VPS4A
20 interacting genes:
CHMP4B
CSNK2A1
DDX39A
DDX39B
DIS3
EXOSC1
EXOSC2
EXOSC3
EXOSC4
EXOSC5
EXOSC6
EXOSC7
EXOSC8
HBS1L
MPHOSPH6
MTREX
PALS2
SUMO2
UBE2I
ZDHHC17
Entrez ID
128866
5393
HPRD ID
16642
07315
Ensembl ID
ENSG00000101421
ENSG00000123737
Uniprot IDs
Q9H444
B4DXG8
Q06265
PDB IDs
3C3Q
3UM3
4ABM
5MK2
2NN6
6D6Q
6D6R
6H25
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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