CHMP4B and CHMP1B

Data Source:
HPRD (two hybrid)

		CHMP4B	CHMP1B
Description		charged multivesicular body protein 4B	charged multivesicular body protein 1B
Image
GO Annotations	Cellular Component	ESCRT III Complex Nucleus Nuclear Envelope Cytoplasm Endosome Multivesicular Body Cytosol Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Late Endosome Membrane Vesicle Extracellular Exosome	ESCRT III Complex Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Membrane Coat Midbody Late Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding	Protein Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Mitotic Cytokinesis Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Autophagy Nucleus Organization Mitotic Metaphase Plate Congression Exit From Mitosis Regulation Of Centrosome Duplication Endosomal Transport Macroautophagy Viral Life Cycle Nuclear Envelope Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Maintenance Of Lens Transparency Viral Budding Via Host ESCRT Complex Viral Budding Regulation Of Viral Process Protein Polymerization Negative Regulation Of Cell Death Midbody Abscission Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Neuron Death Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Autophagosome Assembly	Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Late Endosome To Vacuole Transport Cell Division Midbody Abscission Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Feeling nervous ( 29500382) Loneliness ( 27629369) Offspring birth weight ( 31043758) Refractive error ( 32231278) Stearic acid (18:0) levels ( 23362303)	Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: CHMP1B CHMP3 CHMP4A CHMP4C CHMP5 CHMP6 EXOSC9 HIPK2 NOD2 PDCD6IP PIAS2 PLIN3 PTPN23 STAMBP UBE2I VPS4A	19 interacting genes: CHMP1A CHMP4B CHMP5 CNOT10 KNSTRN MITD1 PICK1 RAB11A RASSF7 SNRNP200 SPAST SSRP1 STAMBP SUCLG1 USP54 USP8 VPS4A VPS4B VTA1
Entrez ID		128866	57132
HPRD ID		16642	12106
Ensembl ID		ENSG00000101421	ENSG00000255112
Uniprot IDs		Q9H444	Q7LBR1
PDB IDs		3C3Q 3UM3 4ABM 5MK2	3EAB 3JC1 4TXQ 4TXR 6E8G 6TZ4 6TZ5 6TZ9
Enriched GO Terms of Interacting Partners?
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