CHMP4B and CHMP4A

Data Source:
HPRD (two hybrid)

		CHMP4B	CHMP4A
Description		charged multivesicular body protein 4B	charged multivesicular body protein 4A
Image
GO Annotations	Cellular Component	ESCRT III Complex Nucleus Nuclear Envelope Cytoplasm Endosome Multivesicular Body Cytosol Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Late Endosome Membrane Vesicle Extracellular Exosome	ESCRT III Complex Nucleus Cytoplasm Endosome Multivesicular Body Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Cytoplasmic Vesicle Membrane Late Endosome Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding
	Biological Process	Mitotic Cytokinesis Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Autophagy Nucleus Organization Mitotic Metaphase Plate Congression Exit From Mitosis Regulation Of Centrosome Duplication Endosomal Transport Macroautophagy Viral Life Cycle Nuclear Envelope Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Maintenance Of Lens Transparency Viral Budding Via Host ESCRT Complex Viral Budding Regulation Of Viral Process Protein Polymerization Negative Regulation Of Cell Death Midbody Abscission Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Neuron Death Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Autophagosome Assembly	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Nucleus Organization Mitotic Metaphase Plate Congression Membrane Invagination Endosomal Transport Macroautophagy Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Protein Polymerization Midbody Abscission Plasma Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagosome Assembly
Pathways		Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Feeling nervous ( 29500382) Loneliness ( 27629369) Offspring birth weight ( 31043758) Refractive error ( 32231278) Stearic acid (18:0) levels ( 23362303)
Interacting Genes		16 interacting genes: CHMP1B CHMP3 CHMP4A CHMP4C CHMP5 CHMP6 EXOSC9 HIPK2 NOD2 PDCD6IP PIAS2 PLIN3 PTPN23 STAMBP UBE2I VPS4A	14 interacting genes: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 NTAQ1 NUTF2 PDCD6IP STAMBP SYT17 TTC19 VPS4A
Entrez ID		128866	29082
HPRD ID		16642	16597
Ensembl ID		ENSG00000101421	ENSG00000254505
Uniprot IDs		Q9H444	Q9BY43
PDB IDs		3C3Q 3UM3 4ABM 5MK2	3C3O 5MK1
Enriched GO Terms of Interacting Partners?
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