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NUDT21 and SNRNP70
Data Source:
HPRD
(in vitro)
NUDT21
SNRNP70
Description
nudix hydrolase 21
small nuclear ribonucleoprotein U1 subunit 70
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
MRNA Cleavage And Polyadenylation Specificity Factor Complex
MRNA Cleavage Factor Complex
Nuclear Body
Centriolar Satellite
Paraspeckles
Nucleus
Nucleoplasm
Spliceosomal Complex
U1 SnRNP
Nuclear Speck
U2-type Prespliceosome
Molecular Function
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
Hydrolase Activity
MRNA 3'-UTR AU-rich Region Binding
Identical Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
RNA Binding
MRNA Binding
Protein Binding
SnRNA Binding
U1 SnRNA Binding
Biological Process
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
MRNA Polyadenylation
MRNA Processing
Posttranscriptional Regulation Of Gene Expression
Cell Differentiation
MRNA 3'-end Processing
Positive Regulation Of MRNA Cleavage
Protein Tetramerization
Protein Heterotetramerization
Pre-mRNA Cleavage Required For Polyadenylation
MRNA Alternative Polyadenylation
Positive Regulation Of MRNA Polyadenylation
Messenger Ribonucleoprotein Complex Assembly
Positive Regulation Of Stem Cell Differentiation
Positive Regulation Of Pro-B Cell Differentiation
MRNA Splicing, Via Spliceosome
Regulation Of ATPase Activity
Regulation Of RNA Splicing
Positive Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of Protein Refolding
Negative Regulation Of Chaperone-mediated Autophagy
Pathways
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Systolic blood pressure (
30224653
)
Interacting Genes
119 interacting genes:
A2M
ATXN1
CARM1
CDC42
CEP126
CLP1
CPSF6
CPSF7
CTNND2
DBN1
DNMT3L
DYNC1I1
EED
EEF1G
ESR1
EXOSC6
F13A1
FAM90A1
FBN3
FLAD1
FUNDC2
GOLGA2
HSF4
IKZF1
ITCH
JMJD1C
KIFAP3
KRT75
MASP1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-2
MIR138-1
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200B
MIR205
MIR206
MIR20A
MIR214
MIR221
MIR25
MIR29A
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-2
MIR9-2
MIR92A1
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MYL6
NEDD4
NGEF
NIF3L1
NTAQ1
POLR2C
PSMF1
PSPC1
PTN
PYCR1
RBM48
RCC1
RNF19A
RPLP1
S100PBP
SEM1
SEMA5B
SF3B1
SHC1
SLC44A1
SNCAIP
SNRNP70
SPAG8
SRPK1
TCERG1
TEPSIN
TLE1
TRA2A
TRIM23
TRIM27
WWOX
ZNF655
ZRANB1
46 interacting genes:
APP
ARSF
CASP3
CDC42
CDKL3
CEP63
CHERP
CLK2
CRP
CTDP1
DDX17
GEMIN2
GTPBP2
HNRNPA2B1
HTATSF1
IL32
IL7R
LRP1
MYC
NUDT21
PRKD2
PRMT5
PRPF40A
RASGRF1
RELA
RNF11
SCAF11
SHBG
SKIL
SMAD1
SMAD2
SMAD3
SMAD4
SMAD5
SMAD9
SMURF2
SNRPC
SRPK1
SRPK2
SRRM4
SRSF1
SRSF10
SRSF2
TOP1
WBP4
ZRANB2
Entrez ID
11051
6625
HPRD ID
05400
01617
Ensembl ID
ENSG00000167005
ENSG00000104852
Uniprot IDs
A0A024R6W2
O43809
A0A024QZD5
P08621
Q9UFS1
PDB IDs
2CL3
2J8Q
3BAP
3BHO
3MDG
3MDI
3N9U
3P5T
3P6Y
3Q2S
3Q2T
5R4P
5R4Q
5R4R
5R4S
5R4T
5R4U
5R64
5R65
5R66
5R67
2L5I
2L5J
3CW1
3PGW
4PJO
4PKD
6QX9
Enriched GO Terms of Interacting Partners
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