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NUDT21 and MIR15A
Data Source:
BioGRID
(unspecified method)
NUDT21
MIR15A
Description
nudix hydrolase 21
microRNA 15a
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
MRNA Cleavage And Polyadenylation Specificity Factor Complex
MRNA Cleavage Factor Complex
Nuclear Body
Centriolar Satellite
Paraspeckles
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Molecular Function
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
Hydrolase Activity
MRNA 3'-UTR AU-rich Region Binding
Identical Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
MRNA Polyadenylation
MRNA Processing
Posttranscriptional Regulation Of Gene Expression
Cell Differentiation
MRNA 3'-end Processing
Positive Regulation Of MRNA Cleavage
Protein Tetramerization
Protein Heterotetramerization
Pre-mRNA Cleavage Required For Polyadenylation
MRNA Alternative Polyadenylation
Positive Regulation Of MRNA Polyadenylation
Messenger Ribonucleoprotein Complex Assembly
Positive Regulation Of Stem Cell Differentiation
Positive Regulation Of Pro-B Cell Differentiation
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Angiogenesis
Negative Regulation Of NF-kappaB Transcription Factor Activity
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Inflammatory Response
Cellular Response To Glucose Stimulus
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Interacting Genes
119 interacting genes:
A2M
ATXN1
CARM1
CDC42
CEP126
CLP1
CPSF6
CPSF7
CTNND2
DBN1
DNMT3L
DYNC1I1
EED
EEF1G
ESR1
EXOSC6
F13A1
FAM90A1
FBN3
FLAD1
FUNDC2
GOLGA2
HSF4
IKZF1
ITCH
JMJD1C
KIFAP3
KRT75
MASP1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-2
MIR138-1
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200B
MIR205
MIR206
MIR20A
MIR214
MIR221
MIR25
MIR29A
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-2
MIR9-2
MIR92A1
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MYL6
NEDD4
NGEF
NIF3L1
NTAQ1
POLR2C
PSMF1
PSPC1
PTN
PYCR1
RBM48
RCC1
RNF19A
RPLP1
S100PBP
SEM1
SEMA5B
SF3B1
SHC1
SLC44A1
SNCAIP
SNRNP70
SPAG8
SRPK1
TCERG1
TEPSIN
TLE1
TRA2A
TRIM23
TRIM27
WWOX
ZNF655
ZRANB1
73 interacting genes:
AIMP1
AIMP2
C1QBP
CPSF1
DARS1
DDX1
DDX21
DDX3X
DDX49
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FUS
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT21
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PUF60
QARS1
RARS1
RBM14
RTCA
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SFPQ
SPOUT1
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM71
TRMT10C
UPF1
UTP20
YBX1
YBX3
ZNF346
Entrez ID
11051
406948
HPRD ID
05400
Ensembl ID
ENSG00000167005
ENSG00000283785
Uniprot IDs
A0A024R6W2
O43809
PDB IDs
2CL3
2J8Q
3BAP
3BHO
3MDG
3MDI
3N9U
3P5T
3P6Y
3Q2S
3Q2T
5R4P
5R4Q
5R4R
5R4S
5R4T
5R4U
5R64
5R65
5R66
5R67
Enriched GO Terms of Interacting Partners
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