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NUDT21 and RPLP1
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
NUDT21
RPLP1
Description
nudix hydrolase 21
ribosomal protein lateral stalk subunit P1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
MRNA Cleavage And Polyadenylation Specificity Factor Complex
MRNA Cleavage Factor Complex
Nuclear Body
Centriolar Satellite
Paraspeckles
Cytosol
Focal Adhesion
Cytosolic Large Ribosomal Subunit
Molecular Function
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
Hydrolase Activity
MRNA 3'-UTR AU-rich Region Binding
Identical Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Structural Constituent Of Ribosome
Protein Binding
Protein Kinase Activator Activity
Ribonucleoprotein Complex Binding
Biological Process
MRNA Splicing, Via Spliceosome
Termination Of RNA Polymerase II Transcription
MRNA Polyadenylation
MRNA Processing
Posttranscriptional Regulation Of Gene Expression
Cell Differentiation
MRNA 3'-end Processing
Positive Regulation Of MRNA Cleavage
Protein Tetramerization
Protein Heterotetramerization
Pre-mRNA Cleavage Required For Polyadenylation
MRNA Alternative Polyadenylation
Positive Regulation Of MRNA Polyadenylation
Messenger Ribonucleoprotein Complex Assembly
Positive Regulation Of Stem Cell Differentiation
Positive Regulation Of Pro-B Cell Differentiation
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Cytoplasmic Translation
Translation
Translational Initiation
Translational Elongation
SRP-dependent Cotranslational Protein Targeting To Membrane
Viral Transcription
Activation Of Protein Kinase Activity
Pathways
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Processing of Intronless Pre-mRNAs
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Chronic lymphocytic leukemia (
28165464
24292274
23770605
)
Male-pattern baldness (
27182965
)
Non-response to citalopram or escitalopram and depression (
27622933
)
Interacting Genes
119 interacting genes:
A2M
ATXN1
CARM1
CDC42
CEP126
CLP1
CPSF6
CPSF7
CTNND2
DBN1
DNMT3L
DYNC1I1
EED
EEF1G
ESR1
EXOSC6
F13A1
FAM90A1
FBN3
FLAD1
FUNDC2
GOLGA2
HSF4
IKZF1
ITCH
JMJD1C
KIFAP3
KRT75
MASP1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-2
MIR138-1
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200B
MIR205
MIR206
MIR20A
MIR214
MIR221
MIR25
MIR29A
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-2
MIR9-2
MIR92A1
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MYL6
NEDD4
NGEF
NIF3L1
NTAQ1
POLR2C
PSMF1
PSPC1
PTN
PYCR1
RBM48
RCC1
RNF19A
RPLP1
S100PBP
SEM1
SEMA5B
SF3B1
SHC1
SLC44A1
SNCAIP
SNRNP70
SPAG8
SRPK1
TCERG1
TEPSIN
TLE1
TRA2A
TRIM23
TRIM27
WWOX
ZNF655
ZRANB1
35 interacting genes:
ANKRD13B
ASCC2
ATP5MF
BRD7
C11orf58
C15orf39
CDIPT
CDK2AP2
CLIC1
CSNK2A1
EEF1A1
GEMIN7
GSK3B
LRIF1
MAP1LC3B
MPC2
NSF
NUDT21
NUDT3
PDCD4
PFDN1
PPP2CB
PTN
RCHY1
RPA2
RPLP2
RPS6KA6
SAT1
SGO1
SUOX
TAB1
TPT1
TUBB2A
UBE2D3
XRCC6
Entrez ID
11051
6176
HPRD ID
05400
01611
Ensembl ID
ENSG00000167005
ENSG00000137818
Uniprot IDs
A0A024R6W2
O43809
A0A024R608
P05386
PDB IDs
2CL3
2J8Q
3BAP
3BHO
3MDG
3MDI
3N9U
3P5T
3P6Y
3Q2S
3Q2T
5R4P
5R4Q
5R4R
5R4S
5R4T
5R4U
5R64
5R65
5R66
5R67
2LBF
4BEH
4V6X
Enriched GO Terms of Interacting Partners
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