SNRNP70 and ZRANB2

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SNRNP70	ZRANB2
Description		small nuclear ribonucleoprotein U1 subunit 70	zinc finger RANBP2-type containing 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck U2-type Prespliceosome	Nucleoplasm
	Molecular Function	RNA Binding MRNA Binding Protein Binding SnRNA Binding U1 SnRNA Binding	Lipopolysaccharide Binding RNA Binding Protein Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of ATPase Activity Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Refolding Negative Regulation Of Chaperone-mediated Autophagy	MRNA Processing RNA Splicing
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Systolic blood pressure ( 30224653)	Dental caries (decayed, missing and filled teeth) ( 31533690) Verbal declarative memory ( 25648963)
Interacting Genes		46 interacting genes: APP ARSF CASP3 CDC42 CDKL3 CEP63 CHERP CLK2 CRP CTDP1 DDX17 GEMIN2 GTPBP2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2	14 interacting genes: AKAP17A CSNK2A1 EP300 KIF20A LRRK2 SMN1 SNRNP70 SREK1 SRPK1 SRPK2 SRSF2 TRA2B U2AF1 YY1
Entrez ID		6625	9406
HPRD ID		01617	09185
Ensembl ID		ENSG00000104852	ENSG00000132485
Uniprot IDs		A0A024QZD5 P08621 Q9UFS1	O95218
PDB IDs		2L5I 2L5J 3CW1 3PGW 4PJO 4PKD 6QX9	1N0Z 2K1P 3G9Y
Enriched GO Terms of Interacting Partners?
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