SNRNP70 and GEMIN2

Data Source:
HPRD (in vitro, two hybrid)

		SNRNP70	GEMIN2
Description		small nuclear ribonucleoprotein U1 subunit 70	gem nuclear organelle associated protein 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U1 SnRNP Nuclear Speck U2-type Prespliceosome	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	RNA Binding MRNA Binding Protein Binding SnRNA Binding U1 SnRNA Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Regulation Of ATPase Activity Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Refolding Negative Regulation Of Chaperone-mediated Autophagy	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Import Into Nucleus
Pathways		mRNA Splicing - Major Pathway	snRNP Assembly
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Systolic blood pressure ( 30224653)	Vitamin D levels ( 28757204)
Interacting Genes		46 interacting genes: APP ARSF CASP3 CDC42 CDKL3 CEP63 CHERP CLK2 CRP CTDP1 DDX17 GEMIN2 GTPBP2 HNRNPA2B1 HTATSF1 IL32 IL7R LRP1 MYC NUDT21 PRKD2 PRMT5 PRPF40A RASGRF1 RELA RNF11 SCAF11 SHBG SKIL SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD9 SMURF2 SNRPC SRPK1 SRPK2 SRRM4 SRSF1 SRSF10 SRSF2 TOP1 WBP4 ZRANB2	34 interacting genes: BEND7 DDX20 DHX9 FBXO7 GEMIN5 HOXD10 IKBKG INCA1 KPNA6 MEOX1 MTNR1A NUFIP1 PAX6 PSMB1 RN7SL1 RNU1-1 RNU2-1 RPP14 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPF SNRPN SPG21 SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2
Entrez ID		6625	8487
HPRD ID		01617	03999
Ensembl ID		ENSG00000104852	ENSG00000092208
Uniprot IDs		A0A024QZD5 P08621 Q9UFS1	O14893
PDB IDs		2L5I 2L5J 3CW1 3PGW 4PJO 4PKD 6QX9	2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU
Enriched GO Terms of Interacting Partners?
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