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MID2 and SPG21
Data Source:
BioGRID
(two hybrid, two hybrid)
MID2
SPG21
Description
midline 2
SPG21 abhydrolase domain containing, maspardin
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Microtubule
Extracellular Exosome
Golgi Apparatus
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Intracellular Membrane-bounded Organelle
Molecular Function
Transcription Coactivator Activity
Microtubule Binding
Zinc Ion Binding
Transferase Activity
Enzyme Binding
Protein Homodimerization Activity
Phosphoprotein Binding
Protein Binding
CD4 Receptor Binding
Biological Process
Positive Regulation Of Autophagy
Protein Ubiquitination
Negative Regulation Of Viral Transcription
Protein Localization To Microtubule
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Viral Entry Into Host Cell
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Viral Release From Host Cell
Antigen Receptor-mediated Signaling Pathway
Pathways
Drugs
Diseases
Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes
238 interacting genes:
ADAMTSL4
AEN
ALDH3B1
ANKS1A
AP1M1
AQP1
ARHGEF5
ATRIP
AXIN1
BAHD1
BCL6B
BLK
BLZF1
BRCA1
BRMS1L
BYSL
C1orf35
CALCOCO2
CARD9
CARHSP1
CBX8
CCDC120
CCDC185
CCDC187
CCDC33
CCDC42
CCHCR1
CDK18
CEP57L1
CFP
CHD2
CNNM3
COX5B
CPSF4
CRACR2A
CREBRF
CTSZ
DCX
DGCR6
DGCR6L
DMRT3
DYDC1
EFHC2
EGFL7
EIF1AD
ELOA
ENKD1
EPN2
ETNK2
FAM107A
FAM161A
FAM161B
FAM214A
FAM214B
FAM50B
FAM90A1
FARS2
FASTKD5
FBF1
FBXL18
FBXW5
FOXD4L3
FRMD6
FSD2
GAS2L2
GAS8
GCC1
GEM
GFI1B
GMCL1
GOLGA2
GOLGA7
GORASP2
GPANK1
GPKOW
GSC2
HAPLN2
HCK
HDAC4
HDX
HNRNPLL
HOXB2
HOXB5
HOXB9
IGBP1
IGFN1
IHO1
IKZF3
IL16
INO80B
IQCN
ISCU
ITGB4
JOSD1
KANK2
KIF1A
KIF9
KIFC3
KRT27
KRT31
KRT40
KRT75
KRT76
LAGE3
LENG1
LGALS14
LGALS8
LMNB2
LMNTD2
LMO3
LMO4
LNX1
LONRF1
LRRC45
LZTS1
LZTS2
MAGEA6
MAGOHB
MEOX1
MEOX2
METTL17
MFAP1
MID1
MID1IP1
MOS
MVP
NCOA4
NR1D2
NSMF
NXF1
OTUB2
PICK1
PKN1
POLDIP3
PPP1R18
PRDM16
PRPF3
PRPF31
PSMA1
PTCD2
PTPDC1
QARS1
RABGEF1
RANBP3L
RCOR3
REL
RLN1
RNF6
RORB
RPH3AL
RPP25L
RUNX1T1
RXRB
SCNM1
SDCBP
SEPTIN1
SHFL
SLC25A48
SLC25A6
SNAI1
SNAP47
SPAG5
SPATA24
SPG21
SPRY2
STX11
SYNGAP1
SYT17
TASOR2
TBC1D22B
TCAF1
TCEA2
TCEANC
TEKT1
THAP7
TMEM14B
TOP3B
TRIM27
TRIM29
TRIM32
TRIM41
TRIM42
TRIM54
TRIM69
TRPV6
TSGA10
TTC23
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E2
UBE2E3
UBE2K
UBE2U
UBTD1
UNC45A
USP2
USP25
USP54
UTP23
UTP25
WT1-AS
ZBTB16
ZBTB24
ZBTB42
ZC2HC1C
ZFYVE21
ZGPAT
ZIM2
ZNF124
ZNF165
ZNF177
ZNF24
ZNF250
ZNF266
ZNF408
ZNF410
ZNF417
ZNF438
ZNF440
ZNF451
ZNF497
ZNF552
ZNF559-ZNF177
ZNF564
ZNF587
ZNF648
ZNF669
ZNF688
ZNF696
ZNF764
ZNF774
ZNF784
ZNF785
ZNF792
ZRANB1
ZSCAN12
164 interacting genes:
ACOT13
AGTR1
AGTRAP
AKIRIN2
APOC1
ARL6IP1
ARL8A
ARMC12
ARMC7
ATP5ME
ATPAF2
BORCS6
BSND
C10orf82
C9orf24
CCDC102B
CCDC153
CCDC33
CCHCR1
CD4
CDK2AP1
CDKN2B
CEP76
CEPT1
CFAP410
CIDEB
CLDN22
CMTM4
CMTM5
CMTM6
COG3
COG6
CPSF7
CRX
CRYAA
CRYAA2
CT55
CTIF
CTPS2
CUTC
DCTPP1
DTX2
DTX3L
EFHC2
EIF1B
EIF4H
EYA2
FAM114A1
FAM86C1P
FBXO44
FLACC1
GAD2
GAS8
GEMIN2
GEMIN4
GGA2
GOLGA2
GOLT1B
GRPEL1
GSK3A
HNRNPH1
HPRT1
HSD17B13
IKZF3
INCA1
IQCB1
KCTD9
KRT13
KRT15
KRT19
KRT31
LEPROTL1
LMNA
LMO1
LNX1
LSMEM2
MAB21L3
MID2
MPC2
MTMR9
MTUS2
MYG1
MYOG
N4BP3
NAB2
NDUFAF2
NIF3L1
NME4
NQO2
NR1D1
NRDE2
NUP54
PAX6
PBX4
PCBD2
PCNA
PDE5A
PEF1
PFDN5
PLP2
PNMA5
PPM1J
PRPS1
PRTFDC1
PSMB4
PTPA
RABAC1
RAD51C
REEP6
REL
ROPN1
RPRD1B
RPS19
RTL8B
RTN4
S100B
SATB1
SCAMP1
SEPTIN5
SFT2D1
SH3GL1
SLC35E3
SORBS3
SPRED1
SPRED2
SRGAP2B
SSBP4
SWSAP1
SYNGR1
SYNGR3
SYP
TCF12
TCF4
TEKT4
TFG
TFIP11
TLE5
TMEM208
TMEM239
TOX2
TPD52
TRAF1
TRAF2
TRIB3
TRIM14
TRIM23
TRIM50
TRIM54
TRIM9
TSGA10IP
TSNAXIP1
TTC23L
TXN
TXNL4B
UFSP1
USHBP1
VMAC
VPS25
YPEL3
ZBTB42
ZMYND12
ZNF263
ZNF581
ZNF629
Entrez ID
11043
51324
HPRD ID
02191
10492
Ensembl ID
ENSG00000080561
ENSG00000090487
Uniprot IDs
Q6GX22
Q9UJV3
A0A024R5Y1
Q9NZD8
PDB IDs
2DJA
2DMK
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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