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PCGF2 and USP11
Data Source:
BioGRID
(pull down)
PCGF2
USP11
Description
polycomb group ring finger 2
ubiquitin specific peptidase 11
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
Nucleus
Nucleoplasm
Chromosome
Cytosol
Molecular Function
DNA Binding
Protein Binding
Metal Ion Binding
Promoter-specific Chromatin Binding
RNA Polymerase II Transcription Corepressor Binding
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Chromatin Silencing
Anterior/posterior Pattern Specification
Histone Acetylation
Histone H2A-K119 Monoubiquitination
Embryonic Skeletal System Morphogenesis
Cellular Response To Hydrogen Peroxide
Negative Regulation Of G0 To G1 Transition
Negative Regulation Of Apoptotic Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Viral Process
Protein Deubiquitination
Protein Phosphopantetheinylation
Pathways
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Transcriptional Regulation by E2F6
Association of TriC/CCT with target proteins during biosynthesis
Ub-specific processing proteases
Drugs
Diseases
GWAS
Interacting Genes
26 interacting genes:
ABHD6
CBX2
CBX6
CCND2
CD247
CTNNAL1
GJB5
HOXC9
HSF2
LMNA
PELI2
PHC1
PHC2
RBCK1
RING1
RNF2
SPDEF
STX2
TRAF2
UBE2D3
UBE2E2
UBE2Q2
UBE2T
UBE2U
USP11
USP7
21 interacting genes:
BMI1
BRCA2
CBX8
CDKN1A
DECR2
EIF4B
LIMS1
LLGL1
MBD3
MTA2
PCGF2
PML
RANBP9
RELB
RNF2
RPS6KB1
SETDB1
SUMO2
TBL3
TP53
UBC
Entrez ID
7703
8237
HPRD ID
10621
02081
Ensembl ID
ENSG00000277258
ENSG00000102226
Uniprot IDs
A0A024R1V6
P35227
B4DGK3
P51784
PDB IDs
4MEL
5OK6
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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