Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
PCGF2 and CBX6
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, pull down)
PCGF2
CBX6
Description
polycomb group ring finger 2
chromobox 6
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
Heterochromatin
Nucleus
Nucleoplasm
PcG Protein Complex
Molecular Function
DNA Binding
Protein Binding
Metal Ion Binding
Promoter-specific Chromatin Binding
Single-stranded RNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Chromatin Silencing
Anterior/posterior Pattern Specification
Histone Acetylation
Histone H2A-K119 Monoubiquitination
Embryonic Skeletal System Morphogenesis
Cellular Response To Hydrogen Peroxide
Negative Regulation Of G0 To G1 Transition
Negative Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Organization
Pathways
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Transcriptional Regulation by E2F6
Oxidative Stress Induced Senescence
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Drugs
Diseases
GWAS
Bladder cancer (
24163127
20972438
)
Plateletcrit (
32888494
)
Interacting Genes
26 interacting genes:
ABHD6
CBX2
CBX6
CCND2
CD247
CTNNAL1
GJB5
HOXC9
HSF2
LMNA
PELI2
PHC1
PHC2
RBCK1
RING1
RNF2
SPDEF
STX2
TRAF2
UBE2D3
UBE2E2
UBE2Q2
UBE2T
UBE2U
USP11
USP7
6 interacting genes:
HOXC9
PCGF1
PCGF2
PCGF3
PCGF5
PCGF6
Entrez ID
7703
23466
HPRD ID
10621
13005
Ensembl ID
ENSG00000277258
ENSG00000183741
Uniprot IDs
A0A024R1V6
P35227
B0QXZ6
O95503
PDB IDs
3GV6
3I90
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?