PCGF2 and UBE2T

Data Source:
BioGRID (two hybrid)

		PCGF2	UBE2T
Description		polycomb group ring finger 2	ubiquitin conjugating enzyme E2 T
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Sex Chromatin Nucleus Nucleoplasm Nuclear Body PcG Protein Complex PRC1 Complex	Nucleus Nucleoplasm Nucleolus
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding Promoter-specific Chromatin Binding	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Chromatin Silencing Anterior/posterior Pattern Specification Histone Acetylation Histone H2A-K119 Monoubiquitination Embryonic Skeletal System Morphogenesis Cellular Response To Hydrogen Peroxide Negative Regulation Of G0 To G1 Transition Negative Regulation Of Apoptotic Signaling Pathway	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Protein Ubiquitination Protein K29-linked Ubiquitination Interstrand Cross-link Repair Protein K27-linked Ubiquitination Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways		SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins Activation of anterior HOX genes in hindbrain development during early embryogenesis Transcriptional Regulation by E2F6	Fanconi Anemia Pathway Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs
Diseases
GWAS			Breast cancer ( 23535733) Celiac disease ( 23936387)
Interacting Genes		26 interacting genes: ABHD6 CBX2 CBX6 CCND2 CD247 CTNNAL1 GJB5 HOXC9 HSF2 LMNA PELI2 PHC1 PHC2 RBCK1 RING1 RNF2 SPDEF STX2 TRAF2 UBE2D3 UBE2E2 UBE2Q2 UBE2T UBE2U USP11 USP7	22 interacting genes: AMFR ARIH2 BRCA1 CDK2 CHEK1 FANCD2 FANCL LNX2 MARCHF5 MGRN1 PCGF2 PRKCG PRKN RNF128 RNF144B RNF31 RNF4 ROCK1 RPS6KA1 TRIM27 UBA1 UBA6
Entrez ID		7703	29089
HPRD ID		10621	13704
Ensembl ID		ENSG00000277258	ENSG00000077152
Uniprot IDs		A0A024R1V6 P35227	A0A024R9A9 Q9NPD8
PDB IDs			1YH2 4CCG 5NGZ 5OJJ 6R75
Enriched GO Terms of Interacting Partners?
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