USP11 and RANBP9

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		USP11	RANBP9
Description		ubiquitin specific peptidase 11	RAN binding protein 9
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Nuclear Body
	Molecular Function	RNA Polymerase II Transcription Corepressor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding	Protein Binding Enzyme Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Viral Process Protein Deubiquitination Protein Phosphopantetheinylation	MAPK Cascade Cytoskeleton Organization Microtubule Nucleation Cell Surface Receptor Signaling Pathway Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Pathways		Association of TriC/CCT with target proteins during biosynthesis Ub-specific processing proteases	L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling
Drugs
Diseases
GWAS			Breast cancer ( 29059683 23535729)
Interacting Genes		21 interacting genes: BMI1 BRCA2 CBX8 CDKN1A DECR2 EIF4B LIMS1 LLGL1 MBD3 MTA2 PCGF2 PML RANBP9 RELB RNF2 RPS6KB1 SETDB1 SUMO2 TBL3 TP53 UBC	56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5
Entrez ID		8237	10048
HPRD ID		02081	04835
Ensembl ID		ENSG00000102226	ENSG00000010017
Uniprot IDs		B4DGK3 P51784	A0A024QZW3 Q96S59
PDB IDs		4MEL 5OK6	5JI7 5JI9 5JIU
Enriched GO Terms of Interacting Partners?
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