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PCGF2 and HOXC9
Data Source:
BioGRID
(two hybrid)
PCGF2
HOXC9
Description
polycomb group ring finger 2
homeobox C9
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Sex Chromatin
Nucleus
Nucleoplasm
Nuclear Body
PcG Protein Complex
PRC1 Complex
Chromatin
Nucleus
Nucleoplasm
Aggresome
Molecular Function
DNA Binding
Protein Binding
Metal Ion Binding
Promoter-specific Chromatin Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Chromatin Silencing
Anterior/posterior Pattern Specification
Histone Acetylation
Histone H2A-K119 Monoubiquitination
Embryonic Skeletal System Morphogenesis
Cellular Response To Hydrogen Peroxide
Negative Regulation Of G0 To G1 Transition
Negative Regulation Of Apoptotic Signaling Pathway
Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Anterior/posterior Pattern Specification
Proximal/distal Pattern Formation
Embryonic Skeletal System Morphogenesis
Pathways
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS
Heel bone mineral density (
30598549
)
Waist-to-hip ratio adjusted for BMI (
26426971
)
Waist-to-hip ratio adjusted for BMI (age <50) (
26426971
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
26 interacting genes:
ABHD6
CBX2
CBX6
CCND2
CD247
CTNNAL1
GJB5
HOXC9
HSF2
LMNA
PELI2
PHC1
PHC2
RBCK1
RING1
RNF2
SPDEF
STX2
TRAF2
UBE2D3
UBE2E2
UBE2Q2
UBE2T
UBE2U
USP11
USP7
29 interacting genes:
CBX6
CYSRT1
ELAVL2
GMNN
GTF2A1L
HOXC13
HOXD1
HOXD9
IRF9
KRTAP6-2
LPXN
MAGED1
MSX2
NFKBID
NMI
PAX6
PAX8
PBX2
PCGF2
POLR2D
POLR3D
POU2AF1
POU2F1
TEX37
TLE5
UFSP1
ZFP36
ZMYND12
ZNF384
Entrez ID
7703
3225
HPRD ID
10621
00857
Ensembl ID
ENSG00000277258
ENSG00000180806
Uniprot IDs
A0A024R1V6
P35227
A0A024RAZ6
P31274
PDB IDs
2LP0
2MSY
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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